U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ztf-3 C2H2-type domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 171617, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
ztf-3
Official Full Name
C2H2-type domain-containing protein
Primary source
WormBase:WBGene00016905
Locus tag
CELE_C53D5.4
See related
AllianceGenome:WB:WBGene00016905
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. Is expressed in several structures, including pharynx and rectum. [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See ztf-3 in Genome Data Viewer
Location:
chromosome: I
Exon count:
6
Sequence:
Chromosome: I; NC_003279.8 (286040..289185, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RING-CH-type domain-containing protein Neighboring gene FAM69 protein-kinase domain-containing protein Neighboring gene Gamma-glutamyltranspeptidase 1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. H3K9me selectively blocks transcription factor activity and ensures differentiated tissue integrity. Methot SP, et al. Nat Cell Biol, 2021 Nov. PMID 34737442, Free PMC Article
  2. The molecular signature and cis-regulatory architecture of a C. elegans gustatory neuron. Etchberger JF, et al. Genes Dev, 2007 Jul 1. PMID 17606643, Free PMC Article
  3. A combined binary interaction and phenotypic map of C. elegans cell polarity proteins. Koorman T, et al. Nat Cell Biol, 2016 Mar. PMID 26780296, Free PMC Article
  4. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
C2H2-type domain-containing protein
NP_001293219.1
  • Confirmed by transcript evidence
NP_001293220.1
  • Confirmed by transcript evidence
NP_001359947.1
  • Confirmed by transcript evidence
NP_001360315.1
  • Confirmed by transcript evidence
NP_001368396.1
  • Confirmed by transcript evidence
NP_001368397.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    286040..289185 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001373725.1 → NP_001359947.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N5V6
    Conserved Domains (2) summary
    sd00017
    Location:233 → 253
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:231 → 253
    zf-C2H2; Zinc finger, C2H2 type

  2. NM_001373713.1 → NP_001360315.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    V6CLP3
    Conserved Domains (2) summary
    sd00017
    Location:233 → 253
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:231 → 253
    zf-C2H2; Zinc finger, C2H2 type

  3. NM_001381400.1 → NP_001368396.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    V6CLN7
    Conserved Domains (2) summary
    sd00017
    Location:220 → 240
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:218 → 240
    zf-C2H2; Zinc finger, C2H2 type

  4. NM_001306291.3 → NP_001293220.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293220.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    V6CKB8
    Conserved Domains (2) summary
    sd00017
    Location:83 → 103
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:81 → 103
    zf-C2H2; Zinc finger, C2H2 type

  5. NM_001381421.1 → NP_001368397.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    V6CLJ4
    Conserved Domains (2) summary
    sd00017
    Location:220 → 240
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:218 → 240
    zf-C2H2; Zinc finger, C2H2 type

  6. NM_001306290.3 → NP_001293219.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293219.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    V6CJ73
    Conserved Domains (2) summary
    sd00017
    Location:83 → 103
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:81 → 103
    zf-C2H2; Zinc finger, C2H2 type
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools