U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

deps-1 P-granule-associated protein deps-1 [ Caenorhabditis elegans ]

Gene ID: 171642, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
deps-1
Official Full Name
P-granule-associated protein deps-1
Primary source
WormBase:WBGene00022034
Locus tag
CELE_Y65B4BL.2
See related
AllianceGenome:WB:WBGene00022034
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in regulatory ncRNA-mediated gene silencing. Located in P granule. Is expressed in germ line and oocyte. [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See deps-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
12
Sequence:
Chromosome: I; NC_003279.8 (506473..509056)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ABC-type antigen peptide transporter Neighboring gene Transmembrane protein Neighboring gene Dolichyl-phosphate-mannose--protein mannosyltransferase Neighboring gene Transmembrane protein Neighboring gene ncRNA Neighboring gene Long-chain-fatty-acid--CoA ligase Neighboring gene ncRNA

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. DEPS-1 promotes P-granule assembly and RNA interference in C. elegans germ cells. Spike CA, et al. Development, 2008 Mar. PMID 18234720, Free PMC Article
  2. GLH/VASA helicases promote germ granule formation to ensure the fidelity of piRNA-mediated transcriptome surveillance. Chen W, et al. Nat Commun, 2022 Sep 9. PMID 36085149, Free PMC Article
  3. Small-RNA-mediated transgenerational silencing of histone genes impairs fertility in piRNA mutants. Barucci G, et al. Nat Cell Biol, 2020 Feb. PMID 32015436, Free PMC Article
  4. 26G endo-siRNAs regulate spermatogenic and zygotic gene expression in Caenorhabditis elegans. Han T, et al. Proc Natl Acad Sci U S A, 2009 Nov 3. PMID 19846761, Free PMC Article
  5. Germ Granules Coordinate RNA-Based Epigenetic Inheritance Pathways. Dodson AE, et al. Dev Cell, 2019 Sep 23. PMID 31402284, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans.
    Title: DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in regulatory ncRNA-mediated gene silencing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in P granule IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
P-granule-associated protein deps-1
NP_001293193.1
  • Confirmed by transcript evidence
NP_490742.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    506473..509056
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058341.6 → NP_490742.1  P-granule-associated protein deps-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_490742.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9N303, V6CLC9

  2. NM_001306264.3 → NP_001293193.1  P-granule-associated protein deps-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293193.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    V6CLC9
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9N303.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools