U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

C53H9.2 Large subunit GTPase 1 homolog [ Caenorhabditis elegans ]

Gene ID: 171749, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
C53H9.2
Official Full Name
Large subunit GTPase 1 homolog
Primary source
WormBase:WBGene00016907
Locus tag
CELE_C53H9.2
See related
AllianceGenome:WB:WBGene00016907
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable GTPase activity. Predicted to be involved in ribosomal subunit export from nucleus. Predicted to be active in cytosol. Orthologous to human LSG1 (large 60S subunit nuclear export GTPase 1). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See C53H9.2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
5
Sequence:
Chromosome: I; NC_003279.8 (1832897..1834763)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene 30S ribosomal protein S18 Neighboring gene Large ribosomal subunit protein eL27 Neighboring gene Variable lymphocyte receptor A cassette Neighboring gene Guanine nucleotide-binding protein subunit alpha

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
  2. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in ribosomal subunit export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Large subunit GTPase 1 homolog
NP_740787.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    1832897..1834763
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_170804.6 → NP_740787.2  Large subunit GTPase 1 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_740787.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    O01826
    Conserved Domains (2) summary
    cd01857
    Location:171 → 356
    HSR1_MMR1; A circularly permuted subfamily of the Ras GTPases
    COG1161
    Location:145 → 476
    RbgA; Ribosome biogenesis GTPase A [Translation, ribosomal structure and biogenesis]

RNA

  1. NR_131349.1 RNA Sequence

    Status: REVIEWED

  2. NR_131350.1 RNA Sequence

    Status: REVIEWED

  3. NR_151555.1 RNA Sequence

    Status: REVIEWED

  4. NR_131348.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools