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W03F11.4 WSN domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 171780, updated on 2-Nov-2024

Summary

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Official Symbol
W03F11.4
Official Full Name
WSN domain-containing protein
Primary source
WormBase:WBGene00021007
Locus tag
CELE_W03F11.4
See related
AllianceGenome:WB:WBGene00021007
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See W03F11.4 in Genome Data Viewer
Location:
chromosome: I
Exon count:
10
Sequence:
Chromosome: I; NC_003279.8 (2235602..2241252, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Receptor-type guanylate cyclase gcy-17 Neighboring gene Major sperm protein Neighboring gene ncRNA Neighboring gene Ligand-Gated ion Channel Neighboring gene MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. C30F12.4 influences oogenesis, fat metabolism, and lifespan in C. elegans. Wang L, et al. Protein Cell, 2016 Oct. PMID 27638466, Free PMC Article
  2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
WSN domain-containing protein
NP_490945.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    2235602..2241252 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058544.6 → NP_490945.2  WSN domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_490945.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    O01777
    Conserved Domains (3) summary
    smart00453
    Location:47 → 113
    WSN; Worm-specific (usually) N-terminal domain
    cd00047
    Location:966 → 1222
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    pfam00102
    Location:966 → 1222
    Y_phosphatase; Protein-tyrosine phosphatase
Nucleotide Protein
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