U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

pid-3 Protein pid-3 [ Caenorhabditis elegans ]

Gene ID: 171819, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
pid-3
Official Full Name
Protein pid-3
Primary source
WormBase:WBGene00021270
Locus tag
CELE_Y23H5A.3
See related
AllianceGenome:WB:WBGene00021270
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in piRNA processing; positive regulation of cell division; and positive regulation of chromosome segregation. Located in nucleus and perinuclear region of cytoplasm. Is expressed in germ line. [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See pid-3 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003279.8 (2620650..2621859)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Alpha-catulin Neighboring gene ncRNA Neighboring gene Major sperm protein Neighboring gene ncRNA Neighboring gene Cnn_1N domain-containing protein;t-SNARE coiled-coil homology domain-containing protein Neighboring gene Cysteine--tRNA ligase, cytoplasmic Neighboring gene pseudo

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Molecular basis for PICS-mediated piRNA biogenesis and cell division. Wang X, et al. Nat Commun, 2021 Sep 22. PMID 34552083, Free PMC Article
  2. Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans. Perez-Borrajero C, et al. Genes Dev, 2021 Sep 1. PMID 34413138, Free PMC Article
  3. Taxonomically Restricted Genes with Essential Functions Frequently Play Roles in Chromosome Segregation in Caenorhabditis elegans and Saccharomyces cerevisiae. Verster AJ, et al. G3 (Bethesda), 2017 Oct 5. PMID 28839119, Free PMC Article
  4. Functional Proteomics Identifies a PICS Complex Required for piRNA Maturation and Chromosome Segregation. Zeng C, et al. Cell Rep, 2019 Jun 18. PMID 31216475
  5. The SNAPc complex mediates starvation-induced trans-splicing in Caenorhabditis elegans. Hou X, et al. J Genet Genomics, 2022 Oct. PMID 35283340

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in chromosome segregation IEA
Inferred from Electronic Annotation
more info
  
involved_in piRNA processing IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of cell division IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of chromosome segregation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulatory ncRNA-mediated gene silencing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Protein pid-3
NP_491011.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    2620650..2621859
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058610.6 → NP_491011.1  Protein pid-3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491011.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O76616
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O76616.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools