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rnf-126 RING-type E3 ubiquitin transferase [ Caenorhabditis elegans ]

Gene ID: 171875, updated on 2-Nov-2024

Summary

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Official Symbol
rnf-126
Official Full Name
RING-type E3 ubiquitin transferase
Primary source
WormBase:WBGene00021842
Locus tag
CELE_Y54E10BR.3
See related
AllianceGenome:WB:WBGene00021842
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Predicted to be active in cytoplasm. Orthologous to human RNF115 (ring finger protein 115) and RNF126 (ring finger protein 126). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See rnf-126 in Genome Data Viewer
Location:
chromosome: I
Exon count:
5
Sequence:
Chromosome: I; NC_003279.8 (3021651..3028396)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Dual specificity mitogen-activated protein kinase kinase mek-2 Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene RNA-binding protein NOB1 Neighboring gene Signal peptidase complex catalytic subunit SEC11 Neighboring gene ADP-ribosylation factor-related protein 1 Neighboring gene DNA-directed RNA polymerase II subunit RPB7 Neighboring gene Transporter

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ubiquitin-mediated pathways in C. elegans. Kipreos ET. WormBook, 2005 Dec 1. PMID 18050424, Free PMC Article
  2. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
RING-type E3 ubiquitin transferase
NP_491091.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    3021651..3028396
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058690.6 → NP_491091.1  RING-type E3 ubiquitin transferase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491091.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N3D1
    Conserved Domains (3) summary
    cd00162
    Location:238 → 278
    RING_Ubox; RING-H2 finger (C3H2C3-type) [structural motif]
    pfam14369
    Location:3 → 33
    zinc_ribbon_9; zinc-ribbon
    cl17238
    Location:237 → 279
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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