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rde-10 RNA interference defective protein 10 [ Caenorhabditis elegans ]

Gene ID: 171923, updated on 2-Nov-2024

Summary

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Official Symbol
rde-10
Official Full Name
RNA interference defective protein 10
Primary source
WormBase:WBGene00021634
Locus tag
CELE_Y47G6A.4
See related
AllianceGenome:WB:WBGene00021634
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in regulation of miRNA-mediated gene silencing; regulation of translation; and regulatory ncRNA-mediated gene silencing. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See rde-10 in Genome Data Viewer
Location:
chromosome: I
Exon count:
11
Sequence:
Chromosome: I; NC_003279.8 (3547071..3552005)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Peptidase M14 carboxypeptidase A domain-containing protein;ShKT domain-containing protein Neighboring gene ncRNA Neighboring gene Tyrosine-protein kinase Neighboring gene Poly(U)-binding-splicing factor rnp-6 Neighboring gene DeHydrogenases, Short chain Neighboring gene ncRNA Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. New insights into siRNA amplification and RNAi. Zhang C, et al. RNA Biol, 2012 Aug. PMID 22858672, Free PMC Article
  2. The DEAD box helicase RDE-12 promotes amplification of RNAi in cytoplasmic foci in C. elegans. Yang H, et al. Curr Biol, 2014 Apr 14. PMID 24684930, Free PMC Article
  3. The RDE-10/RDE-11 complex triggers RNAi-induced mRNA degradation by association with target mRNA in C. elegans. Yang H, et al. Genes Dev, 2012 Apr 15. PMID 22508728, Free PMC Article
  4. Multiple small RNA pathways regulate the silencing of repeated and foreign genes in C. elegans. Fischer SE, et al. Genes Dev, 2013 Dec 15. PMID 24352423, Free PMC Article
  5. New Strains for Tissue-Specific RNAi Studies in Caenorhabditis elegans. Watts JS, et al. G3 (Bethesda), 2020 Nov 5. PMID 32943454, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in regulation of miRNA-mediated gene silencing IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of translation IEA
Inferred from Electronic Annotation
more info
  
involved_in regulatory ncRNA-mediated gene silencing IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
RNA interference defective protein 10
NP_491178.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    3547071..3552005
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058777.7 → NP_491178.1  RNA interference defective protein 10 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491178.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9N3S2
    Conserved Domains (1) summary
    pfam13017
    Location:223 → 440
    Maelstrom; piRNA pathway germ-plasm component
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9N3S2.1

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