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eri-6 Enhanced RNAI (RNA interference) [ Caenorhabditis elegans ]

Gene ID: 172050, updated on 2-Nov-2024

Summary

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Official Symbol
eri-6
Official Full Name
Enhanced RNAI (RNA interference)
Primary source
WormBase:WBGene00016561
Locus tag
CELE_C41D11.1
See related
AllianceGenome:WB:WBGene00016561
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Is expressed in ASIL; ASIR; ASKL; ASKR; and hypodermis. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See eri-6 in Genome Data Viewer
Location:
chromosome: I
Exon count:
15
Sequence:
Chromosome: I; NC_003279.8 (4457375..4469458)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Protein cmt-1 Neighboring gene Enhanced RNAI (RNA interference) Neighboring gene DNA2/NAM7 helicase helicase domain-containing protein Neighboring gene ncRNA Neighboring gene Small integral membrane protein 8 Neighboring gene ncRNA Neighboring gene Receptor-type guanylate cyclase gcy-28 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons. Fischer SEJ, et al. Proc Natl Acad Sci U S A, 2020 Mar 17. PMID 32123111, Free PMC Article
  2. A Small-RNA-Mediated Feedback Loop Maintains Proper Levels of 22G-RNAs in C. elegans. Rogers AK, et al. Cell Rep, 2020 Oct 20. PMID 33086057, Free PMC Article
  3. Tissue specificity of Caenorhabditis elegans enhanced RNA interference mutants. Zhuang JJ, et al. Genetics, 2011 May. PMID 21385728, Free PMC Article
  4. Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7. Fischer SE, et al. Nature, 2008 Sep 25. PMID 18784652, Free PMC Article
  5. Multiple small RNA pathways regulate the silencing of repeated and foreign genes in C. elegans. Fischer SE, et al. Genes Dev, 2013 Dec 15. PMID 24352423, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A Small-RNA-Mediated Feedback Loop Maintains Proper Levels of 22G-RNAs in C. elegans.
    Title: A Small-RNA-Mediated Feedback Loop Maintains Proper Levels of 22G-RNAs in C. elegans.
  2. eri-6 and eri-7 produce separate pre-messenger RNAs (pre-mRNAs) that are trans-spliced to form a functional mRNA, eri-6/7 [eri-6; eri-7]
    Title: Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7.
Submit: New GeneRIF Correction

General gene information

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Markers

General protein information

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Preferred Names
Enhanced RNAI (RNA interference)
NP_001249622.1
  • Product from WormBase gene class eri;
    Confirmed by transcript evidence
NP_001249624.1
  • Product from WormBase gene class eri;
    Confirmed by transcript evidence
NP_001249625.1
  • Confirmed by transcript evidence;
    Product from WormBase gene class eri
NP_001367500.1
  • Product from WormBase gene class eri;
    Confirmed by transcript evidence
NP_001379661.1
  • Product from WormBase gene class eri;
    Confirmed by transcript evidence
NP_001380040.1
  • Confirmed by transcript evidence;
    Product from WormBase gene class eri

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    4457375..4469458
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001262695.4 → NP_001249624.1  Enhanced RNAI (RNA interference) [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001249624.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B5TRE2, G4RZ45

  2. NM_001262696.4 → NP_001249625.1  Enhanced RNAI (RNA interference) [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001249625.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B5TRE2, G4RZ49, G5EET9

  3. NM_001379821.1 → NP_001367500.1  Enhanced RNAI (RNA interference) [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    B5TRE2, G4RZ46

  4. NM_001262693.4 → NP_001249622.1  Enhanced RNAI (RNA interference) [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001249622.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B5TRE2, G4RZ48

  5. NM_001392152.1 → NP_001379661.1  Enhanced RNAI (RNA interference) [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    G4SPR0, G5EDX2
    Conserved Domains (1) summary
    pfam06918
    Location:69 → 272
    DUF1280; Protein of unknown function (DUF1280)

  6. NM_001392154.1 → NP_001380040.1  Enhanced RNAI (RNA interference) [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    G4RZ35
Nucleotide Protein
Heading Accession and Version

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