mat-1 Cell division cycle protein 27 homolog [Caenorhabditis elegans] - Gene

Summary

Go to the top of the page Help

Official Symbol: mat-1
Official Full Name: Cell division cycle protein 27 homolog
Primary source: WormBase:WBGene00003132
Locus tag: CELE_Y110A7A.17
See related: AllianceGenome:WB:WBGene00003132
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Involved in asymmetric cell division; cortical granule exocytosis; and polarity specification of anterior/posterior axis. Predicted to be located in nucleus. Predicted to be part of anaphase-promoting complex. Predicted to be active in cytoplasm. Orthologous to human CDC27 (cell division cycle 27). [provided by Alliance of Genome Resources, Nov 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See mat-1 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 11

Sequence:: Chromosome: I; NC_003279.8 (5123915..5127201, complement)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

Y110A7A.d (e-PCR)
- UniSTS:323442

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in anaphase-promoting complex-dependent catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in asymmetric cell division	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cell division	IBA Inferred from Biological aspect of Ancestor more info
involved_in cell division	IEA Inferred from Electronic Annotation more info
involved_in cortical granule exocytosis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in meiotic cell cycle	IEA Inferred from Electronic Annotation more info
involved_in metaphase/anaphase transition of mitotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
involved_in polarity specification of anterior/posterior axis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein ubiquitination	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein ubiquitination	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of anaphase-promoting complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: Cell division cycle protein 27 homolog

NP_001021714.1

Confirmed by transcript evidence

NP_001364721.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

5123915..5127201 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001377581.3 → NP_001364721.1 Cell division cycle protein 27 homolog [Caenorhabditis elegans]

Status: REVIEWED

Conserved Domains (4) summary

COG0457
Location:453 → 631

TPR; Tetratricopeptide (TPR) repeat [General function prediction only]

TIGR02917
Location:574 → 764

PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein

sd00006
Location:563 → 591

TPR; TPR repeat [structural motif]

pfam12895
Location:39 → 118

ANAPC3; Anaphase-promoting complex, cyclosome, subunit 3
NM_001026543.8 → NP_001021714.1 Cell division cycle protein 27 homolog [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001021714.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q6AW18, Q8T4K4, Q9N593

Conserved Domains (4) summary

sd00006
Location:561 → 589

TPR; TPR repeat [structural motif]

pfam12895
Location:39 → 118

ANAPC3; Anaphase-promoting complex, cyclosome, subunit 3

pfam13414
Location:595 → 660

TPR_11; TPR repeat

pfam14559
Location:675 → 740

TPR_19; Tetratricopeptide repeat