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osr-1 TPR_REGION domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 172161, updated on 2-Nov-2024

Summary

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Official Symbol
osr-1
Official Full Name
TPR_REGION domain-containing protein
Primary source
WormBase:WBGene00016329
Locus tag
CELE_C32E12.3
See related
AllianceGenome:WB:WBGene00016329
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Is expressed in hypodermis and intestine. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See osr-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
8
Sequence:
Chromosome: I; NC_003279.8 (5200259..5203504, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene FANCM (Fanconi anemia complex component M) homolog Neighboring gene putative 3',5'-cyclic phosphodiesterase pde-5 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Transcription factor sem-2 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. p-Coumaric acid improves oxidative and osmosis stress responses in Caenorhabditis elegans. Yue Y, et al. J Sci Food Agric, 2019 Feb. PMID 30047165
  2. Stressed worms: responding to the post-genomics era. Gal TZ, et al. Mol Biochem Parasitol, 2005 Sep. PMID 15955581
  3. Dicarbonyl/L-xylulose reductase (DCXR) producing xylitol regulates egg retention through osmolality control in Caenorhabditis elegans. Kim YN, et al. Anim Cells Syst (Seoul), 2022. PMID 36275448, Free PMC Article
  4. The longevity effect of cranberry extract in Caenorhabditis elegans is modulated by daf-16 and osr-1. Guha S, et al. Age (Dordr), 2013 Oct. PMID 22864793, Free PMC Article
  5. Hormetins, antioxidants and prooxidants: defining quercetin-, caffeic acid- and rosmarinic acid-mediated life extension in C. elegans. Pietsch K, et al. Biogerontology, 2011 Aug. PMID 21503726

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. OSR-1 plays a central role in integrating stress detection and adaptation responses by invoking multiple signaling pathways to promote survival under hyperosmotic environments
    Title: Caenorhabditis elegans OSR-1 regulates behavioral and physiological responses to hyperosmotic environments.
  2. that cranberry supplementation confers increased longevity and stress resistance in C. elegans through pathways modulated by daf-16 and osr-1.
    Title: The longevity effect of cranberry extract in Caenorhabditis elegans is modulated by daf-16 and osr-1.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

General protein information

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Preferred Names
TPR_REGION domain-containing protein
NP_491545.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    5200259..5203504 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059144.7 → NP_491545.2  TPR_REGION domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491545.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EEJ4
Nucleotide Protein
Heading Accession and Version

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