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nath-10 RNA cytidine acetyltransferase [ Caenorhabditis elegans ]

Gene ID: 172182, updated on 2-Nov-2024

Summary

Official Symbol
nath-10
Official Full Name
RNA cytidine acetyltransferase
Primary source
WormBase:WBGene00018866
Locus tag
CELE_F55A12.8
See related
AllianceGenome:WB:WBGene00018866
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable rRNA cytidine N-acetyltransferase activity and tRNA binding activity. Predicted to be involved in rRNA acetylation involved in maturation of SSU-rRNA. Predicted to be located in nucleus. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Is expressed in several structures, including excretory cell; germ line; intestine; pharyngeal-intestinal valve; and rectal gland cell. Orthologous to human NAT10 (N-acetyltransferase 10). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See nath-10 in Genome Data Viewer
Location:
chromosome: I
Exon count:
12
Sequence:
Chromosome: I; NC_003279.8 (5349646..5353774, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Telomere_reg-2 domain-containing protein Neighboring gene 17-beta-hydroxysteroid dehydrogenase type 6 Neighboring gene ncRNA Neighboring gene ncRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables N-acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
Inferred from Electronic Annotation
more info
 
enables rRNA cytidine N-acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables tRNA N-acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables tRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in rRNA acetylation involved in maturation of SSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in rRNA modification IEA
Inferred from Electronic Annotation
more info
 
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in ribosomal small subunit biogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in ribosomal small subunit biogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in tRNA acetylation IEA
Inferred from Electronic Annotation
more info
 
involved_in tRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of small-subunit processome ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
RNA cytidine acetyltransferase
NP_491574.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    5349646..5353774 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059173.5NP_491574.1  RNA cytidine acetyltransferase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491574.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O01757
    Conserved Domains (5) summary
    COG1444
    Location:20914
    TmcA; tRNA(Met) C34 N-acetyltransferase TmcA [Translation, ribosomal structure and biogenesis]
    pfam05127
    Location:279480
    Helicase_RecD; Helicase
    pfam08351
    Location:106200
    DUF1726; Domain of unknown function (DUF1726)
    pfam13718
    Location:521750
    GNAT_acetyltr_2; GNAT acetyltransferase 2
    pfam13725
    Location:780897
    tRNA_bind_2; Possible tRNA binding domain