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zhp-1 Zip homologous protein 1 [ Caenorhabditis elegans ]

Gene ID: 172186, updated on 2-Nov-2024

Summary

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Official Symbol
zhp-1
Official Full Name
Zip homologous protein 1
Primary source
WormBase:WBGene00018867
Locus tag
CELE_F55A12.10
See related
AllianceGenome:WB:WBGene00018867
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable SUMO transferase activity. Predicted to be involved in homologous chromosome pairing at meiosis. Predicted to be located in chromosome. Predicted to be active in synaptonemal complex. Human ortholog(s) of this gene implicated in spermatogenic failure 62. Orthologous to human RNF212 (ring finger protein 212) and RNF212B (ring finger protein 212B). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See zhp-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003279.8 (5366948..5367829, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene PIPK domain-containing protein Neighboring gene DUF1691 domain-containing protein;HEPN domain-containing protein;Transmembrane protein Neighboring gene pseudo Neighboring gene polynucleotide adenylyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A compartmentalized signaling network mediates crossover control in meiosis. Zhang L, et al. Elife, 2018 Mar 9. PMID 29521627, Free PMC Article
  2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables SUMO transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables SUMO transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA recombination IEA
Inferred from Electronic Annotation
more info
  
involved_in homologous chromosome pairing at meiosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in reciprocal meiotic recombination IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
is_active_in synaptonemal complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in synaptonemal complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Zip homologous protein 1
NP_491578.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    5366948..5367829 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059177.6 → NP_491578.1  Zip homologous protein 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491578.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q95R14
    Conserved Domains (3) summary
    PRK03918
    Location:85 → 158
    PRK03918; DNA double-strand break repair ATPase Rad50
    cd00162
    Location:6 → 43
    RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
    pfam14634
    Location:6 → 44
    zf-RING_5; zinc-RING finger domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q95R14.1

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