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C06A5.8 RING-type domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 172276, updated on 2-Nov-2024

Summary

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Official Symbol
C06A5.8
Official Full Name
RING-type domain-containing protein
Primary source
WormBase:WBGene00015505
Locus tag
CELE_C06A5.8
See related
AllianceGenome:WB:WBGene00015505
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Is expressed in germ line and oocyte. Orthologous to human RNF227 (ring finger protein 227). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See C06A5.8 in Genome Data Viewer
Location:
chromosome: I
Exon count:
6
Sequence:
Chromosome: I; NC_003279.8 (6008137..6009524, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene NAD-dependent protein deacetylase sir-2.4 Neighboring gene Tropomodulin Neighboring gene LEM-like domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene RING-type domain-containing protein Neighboring gene Integrator complex subunit 1 RPB2-binding domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Shifted Transversal Design smart-pooling for high coverage interactome mapping. Xin X, et al. Genome Res, 2009 Jul. PMID 19447967, Free PMC Article
  2. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
RING-type domain-containing protein
NP_001379541.1
  • Confirmed by transcript evidence
NP_491737.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    6008137..6009524 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059336.6 → NP_491737.1  RING-type domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491737.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O01481
    Conserved Domains (3) summary
    cd00162
    Location:38 → 83
    RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
    cl00414
    Location:123 → 185
    bS6; Bacterial ribosomal protein S6
    cl17238
    Location:38 → 84
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  2. NM_001392389.1 → NP_001379541.1  RING-type domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q86ND0
    Conserved Domains (1) summary
    cl00414
    Location:55 → 117
    bS6; Bacterial ribosomal protein S6
Nucleotide Protein
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