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rnf-1 RING-type domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 172277, updated on 2-Nov-2024

Summary

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Official Symbol
rnf-1
Official Full Name
RING-type domain-containing protein
Primary source
WormBase:WBGene00004380
Locus tag
CELE_C06A5.9
See related
AllianceGenome:WB:WBGene00004380
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Orthologous to human RNF183 (ring finger protein 183). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See rnf-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
10
Sequence:
Chromosome: I; NC_003279.8 (6009782..6011586, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene LEM-like domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene RING-type domain-containing protein Neighboring gene Integrator complex subunit 1 RPB2-binding domain-containing protein Neighboring gene ncRNA Neighboring gene COP9 signalosome complex subunit 2 Neighboring gene ncRNA Neighboring gene DUF4044 domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of C. elegans RING finger protein 1, a binding partner of ubiquitin-conjugating enzyme 1. Crowe E, et al. Dev Biol, 2004 Jan 15. PMID 14732404
  2. DREAM interrupted: severing LIN-35-MuvB association in Caenorhabditis elegans impairs DREAM function but not its chromatin localization. Goetsch PD, et al. Genetics, 2022 Jul 4. PMID 35554539, Free PMC Article
  3. Interactions within the ubiquitin pathway of Caenorhabditis elegans. Gudgen M, et al. Biochem Biophys Res Commun, 2004 Dec 10. PMID 15530417
  4. Ubiquitin-mediated pathways in C. elegans. Kipreos ET. WormBook, 2005 Dec 1. PMID 18050424, Free PMC Article
  5. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Required for L1 development, vulval development, and for egg laying.
    Title: Characterization of C. elegans RING finger protein 1, a binding partner of ubiquitin-conjugating enzyme 1.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
RING-type domain-containing protein
NP_491738.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    6009782..6011586 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059337.5 → NP_491738.2  RING-type domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491738.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    O01482
    Conserved Domains (2) summary
    cd00162
    Location:22 → 67
    RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
    cl17238
    Location:22 → 68
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
Nucleotide Protein
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