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C48E7.6 Chondroitin sulfate proteoglycan 4 [ Caenorhabditis elegans ]

Gene ID: 172317, updated on 2-Nov-2024

Summary

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Official Symbol
C48E7.6
Official Full Name
Chondroitin sulfate proteoglycan 4
Primary source
WormBase:WBGene00016751
Locus tag
CELE_C48E7.6
See related
AllianceGenome:WB:WBGene00016751
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in anatomical structure morphogenesis. Predicted to be located in membrane. Predicted to be active in collagen-containing extracellular matrix. Human ortholog(s) of this gene implicated in relapsing-remitting multiple sclerosis. Orthologous to human CSPG4 (chondroitin sulfate proteoglycan 4). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See C48E7.6 in Genome Data Viewer
Location:
chromosome: I
Exon count:
30
Sequence:
Chromosome: I; NC_003279.8 (6236134..6249860)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Col_cuticle_N domain-containing protein Neighboring gene MS Related Protein Neighboring gene ncRNA Neighboring gene Saposin B-type domain-containing protein Neighboring gene Olfactomedin-like domain-containing protein Neighboring gene CCAAT/enhancer-binding protein homolog 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in anatomical structure morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in collagen-containing extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Chondroitin sulfate proteoglycan 4
NP_001361945.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    6236134..6249860
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001374899.2 → NP_001361945.1  Chondroitin sulfate proteoglycan 4 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IG72
    Conserved Domains (1) summary
    pfam16184
    Location:1143 → 1247
    Cadherin_3; Cadherin-like
Nucleotide Protein
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