acdh-1 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: acdh-1
Official Full Name: Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
Primary source: WormBase:WBGene00016943
Locus tag: CELE_C55B7.4
See related: AllianceGenome:WB:WBGene00016943
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable acyl-CoA dehydrogenase activity. Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be active in mitochondrion. Is expressed in E lineage cell; hypodermis; intestine; and neurons. Orthologous to human ACADSB (acyl-CoA dehydrogenase short/branched chain). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See acdh-1 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 7

Sequence:: Chromosome: I; NC_003279.8 (6497436..6499560)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C55B7.4 (e-PCR)
- UniSTS:309428

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables acyl-CoA dehydrogenase activity	IBA Inferred from Biological aspect of Ancestor more info
enables flavin adenine dinucleotide binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on the CH-CH group of donors	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in defense response to Gram-negative bacterium	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in innate immune response	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial

NP_001367696.1

Confirmed by transcript evidence

NP_001370604.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

6497436..6499560

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001383261.2 → NP_001370604.1 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

H2KZG6

Conserved Domains (1) summary

cd01158
Location:50 → 420

SCAD_SBCAD; Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases
NM_001380557.1 → NP_001367696.1 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

Q8IAB6

Conserved Domains (1) summary

cl09933
Location:1 → 230

ACAD; Acyl-CoA dehydrogenase