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ipgm-1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [ Caenorhabditis elegans ]

Gene ID: 172376, updated on 2-Nov-2024

Summary

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Official Symbol
ipgm-1
Official Full Name
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Primary source
WormBase:WBGene00019001
Locus tag
CELE_F57B10.3
See related
AllianceGenome:WB:WBGene00019001
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity. Involved in carbohydrate metabolic process. Predicted to be located in cytoplasm. Is expressed in body wall musculature; intestine; and nerve ring. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ipgm-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
9
Sequence:
Chromosome: I; NC_003279.8 (6569557..6572600)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Meiotic spindle formation protein 2 Neighboring gene Protein MRVI1;Thyroid receptor-interacting protein 11 Neighboring gene CREB-H transcription factor homolog let-607 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases. Yu H, et al. Nat Commun, 2017 Apr 3. PMID 28368002, Free PMC Article
  2. Molecular and biochemical characterization of nematode cofactor independent phosphoglycerate mutases. Raverdy S, et al. Mol Biochem Parasitol, 2007 Dec. PMID 17897734
  3. Cofactor-independent phosphoglycerate mutase has an essential role in Caenorhabditis elegans and is conserved in parasitic nematodes. Zhang Y, et al. J Biol Chem, 2004 Aug 27. PMID 15234973
  4. Establishing a blueprint for CED-3-dependent killing through identification of multiple substrates for this protease. Taylor RC, et al. J Biol Chem, 2007 May 18. PMID 17371877
  5. Spatial single-cell sequencing of meiosis I arrested oocytes indicates acquisition of maternal transcripts from the soma. Trimmer KA, et al. Cell Rep, 2023 Jun 27. PMID 37227820, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity IEA
Inferred from Electronic Annotation
more info
  
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables manganese ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables manganese ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphoglycerate mutase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in carbohydrate metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in glucose catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
NP_491896.1
  • Confirmed by transcript evidence
NP_871851.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    6569557..6572600
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059495.6 → NP_491896.1  2,3-bisphosphoglycerate-independent phosphoglycerate mutase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491896.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    G5EFZ1, Q8IA68
    Conserved Domains (2) summary
    PRK05434
    Location:30 → 536
    PRK05434; phosphoglyceromutase; Provisional
    cd16010
    Location:29 → 536
    iPGM; 2 3 bisphosphoglycerate independent phosphoglycerate mutase iPGM

  2. NM_182051.6 → NP_871851.1  2,3-bisphosphoglycerate-independent phosphoglycerate mutase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_871851.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    G5EFZ1
    Conserved Domains (2) summary
    PRK05434
    Location:12 → 518
    PRK05434; phosphoglyceromutase; Provisional
    cd16010
    Location:11 → 518
    iPGM; 2 3 bisphosphoglycerate independent phosphoglycerate mutase iPGM
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
G5EFZ1.1

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