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plin-1 Perilipin-1 homolog [ Caenorhabditis elegans ]

Gene ID: 172437, updated on 18-Sep-2024

Summary

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Official Symbol
plin-1
Official Full Name
Perilipin-1 homolog
Primary source
WormBase:WBGene00007024
Locus tag
CELE_W01A8.1
See related
AllianceGenome:WB:WBGene00007024
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in embryo development. Predicted to be located in lipid droplet. Is expressed in germ line; hypodermal cell; and intestinal cell. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See plin-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
7
Sequence:
Chromosome: I; NC_003279.8 (7057192..7059351)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene DUF19 domain-containing protein Neighboring gene UPF0235 protein Neighboring gene pseudo Neighboring gene ZP domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Perilipin-related protein regulates lipid metabolism in C. elegans. Chughtai AA, et al. PeerJ, 2015. PMID 26357594, Free PMC Article
  2. Systematic, RNA-interference-mediated identification of mus-101 modifier genes in Caenorhabditis elegans. Holway AH, et al. Genetics, 2005 Mar. PMID 15654100, Free PMC Article
  3. Proteomic Interactome of C. elegans Mediator Complex Subunit 28 (MDT-28) Reveals Predominant Association with a Restricted Set of Core Mediator Subunits and an Affinity to Additional Structural and Enzymatic Proteins. Yilma P, et al. Folia Biol (Praha), 2019. PMID 32362303
  4. MDT-28/PLIN-1 mediates lipid droplet-microtubule interaction via DLC-1 in Caenorhabditis elegans. Xie K, et al. Sci Rep, 2019 Oct 17. PMID 31624276, Free PMC Article
  5. Analysis of acidic peptides with a matrix-assisted laser desorption/ionization mass spectrometry using positive and negative ion modes with additive monoammonium phosphate. Nabetani T, et al. Proteomics, 2006 Aug. PMID 16897684

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in embryo development ending in birth or egg hatching IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in lipid droplet IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Perilipin-1 homolog
NP_001021646.1
  • Confirmed by transcript evidence
NP_001021647.1
  • Confirmed by transcript evidence
NP_001122526.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    7057192..7059351
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001129054.5 → NP_001122526.1  Perilipin-1 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122526.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8WHP8, Q23095, Q65ZB1
    Conserved Domains (1) summary
    pfam11594
    Location:246 → 376
    Med28; Mediator complex subunit 28

  2. NM_001026475.4 → NP_001021646.1  Perilipin-1 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021646.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8WHP8
    Conserved Domains (2) summary
    pfam03036
    Location:35 → 69
    Perilipin; Perilipin family
    pfam11594
    Location:243 → 372
    Med28; Mediator complex subunit 28

  3. NM_001026476.5 → NP_001021647.1  Perilipin-1 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021647.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8WHP8
    Conserved Domains (2) summary
    pfam03036
    Location:35 → 69
    Perilipin; Perilipin family
    pfam11594
    Location:243 → 372
    Med28; Mediator complex subunit 28
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A8WHP8.1

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