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plin-1 Perilipin-1 homolog [ Caenorhabditis elegans ]

Gene ID: 172437, updated on 2-Nov-2024

Summary

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Official Symbol
plin-1
Official Full Name
Perilipin-1 homolog
Primary source
WormBase:WBGene00007024
Locus tag
CELE_W01A8.1
See related
AllianceGenome:WB:WBGene00007024
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in embryo development. Predicted to be located in lipid droplet. Is expressed in germ line; hypodermal cell; and intestinal cell. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See plin-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
7
Sequence:
Chromosome: I; NC_003279.8 (7057192..7059351)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene DUF19 domain-containing protein Neighboring gene UPF0235 protein Neighboring gene pseudo Neighboring gene ZP domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Perilipin-related protein regulates lipid metabolism in C. elegans. Chughtai AA, et al. PeerJ, 2015. PMID 26357594, Free PMC Article
  2. Caenorhabditis elegans Perilipin Is Implicated in Cold-Induced Lipolysis and Inhibits Autophagy in Early Embryos. Kassak F, et al. Folia Biol (Praha), 2020. PMID 34087974
  3. A Flexible Network of Lipid Droplet Associated Proteins Support Embryonic Integrity of C. elegans. Cao Z, et al. Front Cell Dev Biol, 2022. PMID 35445028, Free PMC Article
  4. Systematic, RNA-interference-mediated identification of mus-101 modifier genes in Caenorhabditis elegans. Holway AH, et al. Genetics, 2005 Mar. PMID 15654100, Free PMC Article
  5. Proteomic Interactome of C. elegans Mediator Complex Subunit 28 (MDT-28) Reveals Predominant Association with a Restricted Set of Core Mediator Subunits and an Affinity to Additional Structural and Enzymatic Proteins. Yilma P, et al. Folia Biol (Praha), 2019. PMID 32362303

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in embryo development ending in birth or egg hatching IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in lipid droplet IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Perilipin-1 homolog
NP_001021646.1
  • Confirmed by transcript evidence
NP_001021647.1
  • Confirmed by transcript evidence
NP_001122526.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    7057192..7059351
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001129054.5 → NP_001122526.1  Perilipin-1 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122526.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8WHP8, Q23095, Q65ZB1
    Conserved Domains (1) summary
    pfam11594
    Location:246 → 376
    Med28; Mediator complex subunit 28

  2. NM_001026475.4 → NP_001021646.1  Perilipin-1 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021646.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8WHP8
    Conserved Domains (2) summary
    pfam03036
    Location:35 → 69
    Perilipin; Perilipin family
    pfam11594
    Location:243 → 372
    Med28; Mediator complex subunit 28

  3. NM_001026476.5 → NP_001021647.1  Perilipin-1 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021647.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8WHP8
    Conserved Domains (2) summary
    pfam03036
    Location:35 → 69
    Perilipin; Perilipin family
    pfam11594
    Location:243 → 372
    Med28; Mediator complex subunit 28
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A8WHP8.1

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