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eat-5 Innexin eat-5 [ Caenorhabditis elegans ]

Gene ID: 172480, updated on 2-Nov-2024

Summary

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Official Symbol
eat-5
Official Full Name
Innexin eat-5
Primary source
WormBase:WBGene00001136
Locus tag
CELE_F13G3.8
See related
AllianceGenome:WB:WBGene00001136
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable gap junction hemi-channel activity. Predicted to be involved in monoatomic ion transmembrane transport. Predicted to be active in gap junction and plasma membrane. Is expressed in K' cell and pharynx. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See eat-5 in Genome Data Viewer
Location:
chromosome: I
Exon count:
9
Sequence:
Chromosome: I; NC_003279.8 (7308643..7311915, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene SLC (SoLute Carrier) homolog Neighboring gene Ribosomal protein L13 Neighboring gene MIF-like protein mif-3 Neighboring gene Nascent polypeptide-associated complex subunit alpha-like UBA domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. eat-5 and unc-7 represent a multigene family in Caenorhabditis elegans involved in cell-cell coupling. Starich TA, et al. J Cell Biol, 1996 Jul. PMID 8707836, Free PMC Article
  2. Innexin-3 forms connexin-like intercellular channels. Landesman Y, et al. J Cell Sci, 1999 Jul. PMID 10381394
  3. The ionic dependence of voltage-activated inward currents in the pharyngeal muscle of Caenorhabditis elegans. Vinogradova I, et al. Invert Neurosci, 2006 Jun. PMID 16622683
  4. Drosophila Shaking-B protein forms gap junctions in paired Xenopus oocytes. Phelan P, et al. Nature, 1998 Jan 8. PMID 9428764
  5. Control of lifespan by food bacteria, nutrient limitation and pathogenicity of food in C. elegans. So S, et al. Mech Ageing Dev, 2011 Apr. PMID 21354440

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables gap junction channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables gap junction channel activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables gap junction hemi-channel activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in gap junction IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in gap junction IEA
Inferred from Electronic Annotation
more info
  
located_in gap junction ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
Innexin eat-5
NP_492068.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    7308643..7311915 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059667.8 → NP_492068.1  Innexin eat-5 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492068.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q27295
    Conserved Domains (1) summary
    pfam00876
    Location:16 → 384
    Innexin; Innexin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q27295.1

Gene LinkOut

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