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lron-9 eLRR (extracellular Leucine-Rich Repeat) ONly [ Caenorhabditis elegans ]

Gene ID: 172529, updated on 2-Nov-2024

Summary

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Official Symbol
lron-9
Official Full Name
eLRR (extracellular Leucine-Rich Repeat) ONly
Primary source
WormBase:WBGene00011971
Locus tag
CELE_T23G11.6
See related
AllianceGenome:WB:WBGene00011971
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in cell development. Predicted to be located in membrane. Is expressed in head neurons; muscle cell; seam cell; and ventral cord neurons. Orthologous to human LRG1 (leucine rich alpha-2-glycoprotein 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See lron-9 in Genome Data Viewer
Location:
chromosome: I
Exon count:
13
Sequence:
Chromosome: I; NC_003279.8 (7685066..7689403, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Golgin-84 Neighboring gene HAUS6_N domain-containing protein;Vacuolar protein sorting-associated protein VTA1 homolog Neighboring gene Rho-GAP domain-containing protein Neighboring gene Hepatocellular carcinoma-associated antigen 59 Neighboring gene Female germline-specific tumor suppressor gld-1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. IGLR-2, a Leucine-Rich Repeat Domain Containing Protein, Is Required for the Host Defense in Caenorhabditis elegans. Kuo CJ, et al. Front Immunol, 2020. PMID 33329523, Free PMC Article
  2. C. elegans BLMP-1 controls apical epidermal cell morphology by repressing expression of mannosyltransferase bus-8 and molting signal mlt-8. Wu YZ, et al. Dev Biol, 2022 Jun. PMID 35367457
  3. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
  4. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in cell development IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
eLRR (extracellular Leucine-Rich Repeat) ONly
NP_001021638.1
  • Product from WormBase gene class lron;
    Partially confirmed by transcript evidence
NP_001076615.1
  • Product from WormBase gene class lron;
    Confirmed by transcript evidence
NP_001122522.1
  • Product from WormBase gene class lron;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    7685066..7689403 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001083146.7 → NP_001076615.1  eLRR (extracellular Leucine-Rich Repeat) ONly [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001076615.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O02329
    Conserved Domains (3) summary
    cd00116
    Location:234 → 456
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:160 → 183
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:280 → 340
    LRR_8; Leucine rich repeat

  2. NM_001129050.4 → NP_001122522.1  eLRR (extracellular Leucine-Rich Repeat) ONly [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122522.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A5JYW0

  3. NM_001026467.6 → NP_001021638.1  eLRR (extracellular Leucine-Rich Repeat) ONly [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021638.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q58A95
    Conserved Domains (3) summary
    cd00116
    Location:234 → 456
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:160 → 183
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:280 → 340
    LRR_8; Leucine rich repeat

RNA

  1. NR_050271.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version

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