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glb-26 Globin-like protein 26 [ Caenorhabditis elegans ]

Gene ID: 172564, updated on 2-Nov-2024

Summary

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Official Symbol
glb-26
Official Full Name
Globin-like protein 26
Primary source
WormBase:WBGene00011913
Locus tag
CELE_T22C1.2
See related
AllianceGenome:WB:WBGene00011913
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable oxygen binding activity and oxygen carrier activity. Predicted to be involved in oxygen transport and response to hypoxia. Located in membrane and nuclear lamina. Is expressed in anal depressor muscle; head mesodermal cell; intestinal muscle; and in male. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See glb-26 in Genome Data Viewer
Location:
chromosome: I
Exon count:
5
Sequence:
Chromosome: I; NC_003279.8 (7937438..7938487, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Neuroblastoma-amplified sequence Neighboring gene Myosin-11 Neighboring gene UBR-type domain-containing protein Neighboring gene GPI transamidase component GAB1 Neighboring gene Ctf8 Neighboring gene TFIIIC_sub6 domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An N-myristoylated globin with a redox-sensing function that regulates the defecation cycle in Caenorhabditis elegans. Tilleman L, et al. PLoS One, 2012. PMID 23251335, Free PMC Article
  2. Globin-like proteins in Caenorhabditis elegans: in vivo localization, ligand binding and structural properties. Geuens E, et al. BMC Biochem, 2010 Apr 2. PMID 20361867, Free PMC Article
  3. Electron transfer function versus oxygen delivery: a comparative study for several hexacoordinated globins across the animal kingdom. Kiger L, et al. PLoS One, 2011. PMID 21674044, Free PMC Article
  4. Globins in Caenorhabditis elegans. Tilleman L, et al. IUBMB Life, 2011 Mar. PMID 21445847
  5. The Caenorhabditis globin gene family reveals extensive nematode-specific radiation and diversification. Hoogewijs D, et al. BMC Evol Biol, 2008 Oct 9. PMID 18844991, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Phenotypical studies show that GLB-26 takes part in regulating the length of the defecation cycle in C. elegans under oxidative stress conditions.
    Title: An N-myristoylated globin with a redox-sensing function that regulates the defecation cycle in Caenorhabditis elegans.
  2. Caenorhabditis elegans globin GLB-26 (expressed from gene T22C1.2) has been studied in comparison with human neuroglobin (Ngb) and cytoglobin (Cygb) for its electron transfer properties
    Title: Electron transfer function versus oxygen delivery: a comparative study for several hexacoordinated globins across the animal kingdom.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables oxygen binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxygen binding IEA
Inferred from Electronic Annotation
more info
  
enables oxygen carrier activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxygen carrier activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in oxygen transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in oxygen transport IEA
Inferred from Electronic Annotation
more info
  
involved_in response to hypoxia IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nuclear lamina IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nuclear lamina IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Globin-like protein 26
NP_492188.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    7937438..7938487 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059787.4 → NP_492188.1  Globin-like protein 26 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492188.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q22663
    Conserved Domains (1) summary
    cd01040
    Location:35 → 161
    Mb_like; myoglobin_like; M family globin domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q22663.1

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