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T01G9.2 PHAF1 protein T01G9.2 [ Caenorhabditis elegans ]

Gene ID: 172609, updated on 2-Nov-2024

Summary

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Official Symbol
T01G9.2
Official Full Name
PHAF1 protein T01G9.2
Primary source
WormBase:WBGene00011344
Locus tag
CELE_T01G9.2
See related
AllianceGenome:WB:WBGene00011344
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in Golgi to plasma membrane protein transport. Located in striated muscle dense body. Orthologous to human PHAF1 (phagosome assembly factor 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See T01G9.2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
12
Sequence:
Chromosome: I; NC_003279.8 (8275665..8288124, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene NAM-associated domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ZP domain-containing protein Neighboring gene LRRCT domain-containing protein Neighboring gene Casein kinase II subunit beta Neighboring gene Nuclear pore complex protein Nup85

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. C16ORF70/MYTHO promotes healthy aging in C.elegans and prevents cellular senescence in mammals. Franco-Romero A, et al. J Clin Invest, 2024 Jun 13. PMID 38869949, Free PMC Article
  2. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
  3. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article
  4. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  5. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. C16ORF70/MYTHO promotes healthy aging in C.elegans and prevents cellular senescence in mammals.
    Title: C16ORF70/MYTHO promotes healthy aging in C.elegans and prevents cellular senescence in mammals.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in Golgi to plasma membrane protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in phagophore assembly site IEA
Inferred from Electronic Annotation
more info
  
located_in phagophore assembly site ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in striated muscle dense body HDA PubMed 
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
PHAF1 protein T01G9.2
NP_492252.1
  • Confirmed by transcript evidence
NP_740894.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    8275665..8288124 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059851.6 → NP_492252.1  PHAF1 protein T01G9.2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492252.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34692
    Conserved Domains (1) summary
    pfam03676
    Location:30 → 413
    UPF0183; uncharacterized protein family (UPF0183)

  2. NM_171841.9 → NP_740894.1  PHAF1 protein T01G9.2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_740894.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34692, Q22076, Q9U383
    Conserved Domains (1) summary
    pfam03676
    Location:33 → 416
    UPF0183; uncharacterized protein family (UPF0183)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34692.3

Gene LinkOut

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