rpb-3 DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: rpb-3
Official Full Name: DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein
Primary source: WormBase:WBGene00007971
Locus tag: CELE_C36B1.3
See related: AllianceGenome:WB:WBGene00007971
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable DNA-directed 5'-3' RNA polymerase activity and protein dimerization activity. Predicted to contribute to RNA polymerase II activity. Predicted to be involved in transcription by RNA polymerase II. Predicted to be part of RNA polymerase II, core complex. Orthologous to human POLR2C (RNA polymerase II subunit C). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See rpb-3 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 6

Sequence:: Chromosome: I; NC_003279.8 (8728764..8730054)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C36B1.3 (e-PCR)
- UniSTS:307312

C36B1.4 (e-PCR)
- UniSTS:306583

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables DNA-directed 5'-3' RNA polymerase activity	IEA Inferred from Electronic Annotation more info
contributes_to RNA polymerase II activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of DNA-directed RNA polymerase complex	IEA Inferred from Electronic Annotation more info
part_of RNA polymerase II, core complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein

NP_492361.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

8728764..8730054

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_059960.8 → NP_492361.2 DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_492361.2

Status: REVIEWED

UniProtKB/TrEMBL

Q93338

Conserved Domains (1) summary

cd07031
Location:7 → 274

RNAP_II_RPB3; RPB3 subunit of Eukaryotic RNA polymerase II