snpc-4 snRNA-activating protein complex subunit 4 homolog [Caenorhabditis elegans] - Gene

Summary

Go to the top of the page Help

Official Symbol: snpc-4
Official Full Name: snRNA-activating protein complex subunit 4 homolog
Primary source: WormBase:WBGene00001568
Locus tag: CELE_F32H2.1
See related: AllianceGenome:WB:WBGene00001568
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable RNA polymerase III type 3 promoter sequence-specific DNA binding activity. Predicted to contribute to RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in protein folding. Predicted to be located in nucleus. Predicted to be part of snRNA-activating protein complex. Is expressed in germ cell; germ line; head neurons; intestine; and somatic gonad. Orthologous to human SNAPC4 (small nuclear RNA activating complex polypeptide 4). [provided by Alliance of Genome Resources, Nov 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See snpc-4 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 13

Sequence:: Chromosome: I; NC_003279.8 (8962322..8966129)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

SNPC-4 binding establishes a positive expression environment across piRNA domains, providing an explanation for the conserved clustering of individually transcribed piRNA genes.
Title: The C. elegans SNAPc component SNPC-4 coats piRNA domains and is globally required for piRNA abundance.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

F32H2.1 (e-PCR)
- UniSTS:317482

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
contributes_to RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase III type 3 promoter sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in protein folding	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in snRNA transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in snRNA transcription by RNA polymerase III	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of snRNA-activating protein complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: snRNA-activating protein complex subunit 4 homolog

NP_492411.1

Partially confirmed by transcript evidence

NP_492412.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

8962322..8966129

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_060011.5 → NP_492412.1 snRNA-activating protein complex subunit 4 homolog [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_492412.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P91868

Conserved Domains (4) summary

smart00717
Location:357 → 404

SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains

cd00167
Location:411 → 455

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

pfam00249
Location:356 → 402

Myb_DNA-binding; Myb-like DNA-binding domain

cl21498
Location:219 → 261

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
NM_060010.6 → NP_492411.1 snRNA-activating protein complex subunit 4 homolog [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_492411.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O62208, P91868

Conserved Domains (4) summary

smart00717
Location:357 → 404

SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains

cd00167
Location:411 → 455

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

pfam00249
Location:356 → 402

Myb_DNA-binding; Myb-like DNA-binding domain

cl21498
Location:219 → 261

SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...