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rig-5 Ig-like domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 172791, updated on 2-Nov-2024

Summary

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Official Symbol
rig-5
Official Full Name
Ig-like domain-containing protein
Primary source
WormBase:WBGene00004372
Locus tag
CELE_C36F7.4
See related
AllianceGenome:WB:WBGene00004372
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be active in neuron projection. Is expressed in g1; intestine; and neurons. Human ortholog(s) of this gene implicated in ovarian cancer. Orthologous to several human genes including IGLON5 (IgLON family member 5); LSAMP (limbic system associated membrane protein); and NEGR1 (neuronal growth regulator 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See rig-5 in Genome Data Viewer
Location:
chromosome: I
Exon count:
13
Sequence:
Chromosome: I; NC_003279.8 (9565389..9574377, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene tRNA-Ile Neighboring gene tRNA-Ile Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Collagen triple helix repeat protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. wrk-1 and rig-5 control pioneer and follower axon navigation in the ventral nerve cord of Caenorhabditis elegans in a nid-1 mutant background. Feresten AH, et al. Genetics, 2023 Mar 2. PMID 36573271, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. wrk-1 and rig-5 control pioneer and follower axon navigation in the ventral nerve cord of Caenorhabditis elegans in a nid-1 mutant background.
    Title: wrk-1 and rig-5 control pioneer and follower axon navigation in the ventral nerve cord of Caenorhabditis elegans in a nid-1 mutant background.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Ig-like domain-containing protein
NP_001122427.1
  • Partially confirmed by transcript evidence
NP_001122428.1
  • Confirmed by transcript evidence
NP_001251129.1
  • Partially confirmed by transcript evidence
NP_001251131.1
  • Partially confirmed by transcript evidence
NP_001251132.1
  • Confirmed by transcript evidence
NP_001366862.1
  • Confirmed by transcript evidence
NP_492535.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    9565389..9574377 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001264200.4 → NP_001251129.1  Ig-like domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001251129.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2FLI8
    Conserved Domains (3) summary
    smart00409
    Location:294 → 380
    IG; Immunoglobulin
    smart00410
    Location:92 → 189
    IG_like; Immunoglobulin like
    pfam13927
    Location:191 → 270
    Ig_3; Immunoglobulin domain

  2. NM_001381092.1 → NP_001366862.1  Ig-like domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q93350
    Conserved Domains (4) summary
    smart00410
    Location:2 → 93
    IG_like; Immunoglobulin like
    pfam13927
    Location:143 → 225
    Ig_3; Immunoglobulin domain
    cd00096
    Location:146 → 152
    Ig; Ig strand A' [structural motif]
    cl11960
    Location:87 → 140
    Ig; Immunoglobulin domain

  3. NM_060134.4 → NP_492535.1  Ig-like domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492535.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NAR0
    Conserved Domains (2) summary
    smart00409
    Location:92 → 183
    IG; Immunoglobulin
    smart00410
    Location:240 → 326
    IG_like; Immunoglobulin like

  4. NM_001264203.2 → NP_001251132.1  Ig-like domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001251132.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2FLI7
    Conserved Domains (2) summary
    smart00409
    Location:243 → 329
    IG; Immunoglobulin
    smart00410
    Location:147 → 233
    IG_like; Immunoglobulin like

  5. NM_001128955.4 → NP_001122427.1  Ig-like domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122427.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A7UQ11
    Conserved Domains (3) summary
    smart00409
    Location:294 → 380
    IG; Immunoglobulin
    smart00410
    Location:92 → 189
    IG_like; Immunoglobulin like
    pfam13927
    Location:191 → 270
    Ig_3; Immunoglobulin domain

  6. NM_001264202.1 → NP_001251131.1  Ig-like domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001251131.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    C6KRM7
    Conserved Domains (3) summary
    smart00409
    Location:294 → 380
    IG; Immunoglobulin
    smart00410
    Location:92 → 189
    IG_like; Immunoglobulin like
    pfam13927
    Location:191 → 270
    Ig_3; Immunoglobulin domain

  7. NM_001128956.4 → NP_001122428.1  Ig-like domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122428.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B2D6P2
    Conserved Domains (1) summary
    smart00410
    Location:34 → 120
    IG_like; Immunoglobulin like
Nucleotide Protein
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