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F26E4.3 putative peptidase C1-like protein F26E4.3 [ Caenorhabditis elegans ]

Gene ID: 172827, updated on 2-Nov-2024

Summary

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Official Symbol
F26E4.3
Official Full Name
putative peptidase C1-like protein F26E4.3
Primary source
WormBase:WBGene00009158
Locus tag
CELE_F26E4.3
See related
AllianceGenome:WB:WBGene00009158
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable cysteine-type peptidase activity. Predicted to be an extracellular matrix structural constituent. Predicted to be involved in proteolysis. Predicted to be located in collagen-containing extracellular matrix and extracellular region. Predicted to be active in extracellular space and lysosome. Orthologous to several human genes including TINAGL1 (tubulointerstitial nephritis antigen like 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See F26E4.3 in Genome Data Viewer
Location:
chromosome: I
Exon count:
12
Sequence:
Chromosome: I; NC_003279.8 (9762403..9767846, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Serine/threonine-protein phosphatase 2A regulatory subunit sur-6 Neighboring gene Tnp_DDE_dom domain-containing protein Neighboring gene Tyrosine-protein kinase Neighboring gene DNA-directed RNA polymerase III subunit RPC4 Neighboring gene Cytochrome c oxidase polypeptide VIIc

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The in-silico characterization of the Caenorhabditis elegans matrisome and proposal of a novel collagen classification. Teuscher AC, et al. Matrix Biol Plus, 2019 Feb. PMID 33543001, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables cysteine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables extracellular matrix structural constituent RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in collagen-containing extracellular matrix RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in lysosome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
putative peptidase C1-like protein F26E4.3
NP_492593.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    9762403..9767846 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_060192.9 → NP_492593.2  putative peptidase C1-like protein F26E4.3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492593.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P90850
    Conserved Domains (2) summary
    cd02620
    Location:185 → 428
    Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
    pfam01033
    Location:37 → 82
    Somatomedin_B; Somatomedin B domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P90850.3

Gene LinkOut

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