rae-1 mRNA export factor rae-1 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: rae-1
Official Full Name: mRNA export factor rae-1
Primary source: WormBase:WBGene00003803
Locus tag: CELE_F10G8.3
See related: AllianceGenome:WB:WBGene00003803
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable RNA binding activity and ubiquitin binding activity. Predicted to be involved in RNA export from nucleus and transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery. Predicted to be located in axon; nucleus; and synapse. Predicted to be part of nuclear pore. Orthologous to human RAE1 (ribonucleic acid export 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See rae-1 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 4

Sequence:: Chromosome: I; NC_003279.8 (10026643..10030058)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F10G8.3 (e-PCR)
- UniSTS:309678

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in RNA export from nucleus	IBA Inferred from Biological aspect of Ancestor more info
involved_in mRNA transport	IEA Inferred from Electronic Annotation more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info
involved_in transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in axon	IEA Inferred from Electronic Annotation more info
located_in cell projection	IEA Inferred from Electronic Annotation more info
part_of nuclear pore	IBA Inferred from Biological aspect of Ancestor more info
part_of nuclear pore	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in synapse	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: mRNA export factor rae-1

NP_492650.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

10026643..10030058

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_060249.4 → NP_492650.1 mRNA export factor rae-1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_492650.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q93454

Conserved Domains (3) summary

COG2319
Location:42 → 342

WD40; WD40 repeat [General function prediction only]

sd00039
Location:45 → 89

7WD40; WD40 repeat [structural motif]

cl02567
Location:47 → 336

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...