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ZC434.4 Ribosomal RNA-processing protein 7 homolog [ Caenorhabditis elegans ]

Gene ID: 172902, updated on 2-Nov-2024

Summary

Official Symbol
ZC434.4
Official Full Name
Ribosomal RNA-processing protein 7 homolog
Primary source
WormBase:WBGene00013892
Locus tag
CELE_ZC434.4
See related
AllianceGenome:WB:WBGene00013892
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in rRNA processing and ribosomal small subunit assembly. Predicted to be part of CURI complex and UTP-C complex. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Orthologous to several human genes including RRP7A (ribosomal RNA processing 7 homolog A). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See ZC434.4 in Genome Data Viewer
Location:
chromosome: I
Exon count:
5
Sequence:
Chromosome: I; NC_003279.8 (10331979..10333082, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene DUF4477 domain-containing protein Neighboring gene Small ribosomal subunit protein eS7 Neighboring gene DUF3421 domain-containing protein Neighboring gene DUF3421 domain-containing protein

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in ribosomal small subunit assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of CURI complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of UTP-C complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Ribosomal RNA-processing protein 7 homolog
NP_492709.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    10331979..10333082 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_060308.7NP_492709.2  Ribosomal RNA-processing protein 7 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492709.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q23314
    Conserved Domains (1) summary
    cd12951
    Location:143269
    RRP7_Rrp7A; RRP7 domain ribosomal RNA-processing protein 7 homolog A (Rrp7A) and similar proteins