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tag-353 Ubiquitin-like domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 172916, updated on 2-Nov-2024

Summary

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Official Symbol
tag-353
Official Full Name
Ubiquitin-like domain-containing protein
Primary source
WormBase:WBGene00009112
Locus tag
CELE_F25D7.2
See related
AllianceGenome:WB:WBGene00009112
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in membrane. Orthologous to several human genes including HERPUD2 (HERPUD family member 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tag-353 in Genome Data Viewer
Location:
chromosome: I
Exon count:
5
Sequence:
Chromosome: I; NC_003279.8 (10401064..10402762)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of innate immunity genes and pathways using a comparative genomics approach. Alper S, et al. Proc Natl Acad Sci U S A, 2008 May 13. PMID 18463287, Free PMC Article
  2. Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans. Shen X, et al. PLoS Genet, 2005 Sep. PMID 16184190, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
acts_upstream_of_or_within IRE1-mediated unfolded protein response HEP PubMed 
involved_in endoplasmic reticulum unfolded protein response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in response to unfolded protein IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Ubiquitin-like domain-containing protein
NP_492722.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    10401064..10402762
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_060321.7 → NP_492722.2  Ubiquitin-like domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492722.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q93559
    Conserved Domains (1) summary
    cl28922
    Location:18 → 97
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
Nucleotide Protein
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