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mtx-1 Metaxin-1 homolog [ Caenorhabditis elegans ]

Gene ID: 173340, updated on 2-Nov-2024

Summary

Official Symbol
mtx-1
Official Full Name
Metaxin-1 homolog
Primary source
WormBase:WBGene00009559
Locus tag
CELE_F39B2.11
See related
AllianceGenome:WB:WBGene00009559
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in mitochondrion organization. Predicted to be located in mitochondrial outer membrane. Predicted to be part of SAM complex. Predicted to be active in cytoplasm. Orthologous to several human genes including MTX3 (metaxin 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See mtx-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003279.8 (14755154..14756412, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene WD_REPEATS_REGION domain-containing protein Neighboring gene F-box/LRR-repeat protein Neighboring gene DNaJ domain (prokaryotic heat shock protein) Neighboring gene Transmembrane protein 107 Neighboring gene ncRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in mitochondrion organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mitochondrion organization IEA
Inferred from Electronic Annotation
more info
 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of SAM complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of SAM complex IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Metaxin-1 homolog
NP_493569.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    14755154..14756412 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_061168.7NP_493569.1  Metaxin-1 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_493569.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O45503
    Conserved Domains (2) summary
    cd03212
    Location:106231
    GST_C_Metaxin1_3; C-terminal, alpha helical domain of Metaxin 1, Metaxin 3, and similar proteins
    cd03078
    Location:176
    GST_N_Metaxin1_like; GST_N family, Metaxin subfamily, Metaxin 1-like proteins; composed of metaxins 1 and 3, and similar proteins including Tom37 from fungi. Mammalian metaxin (or metaxin 1) and the fungal protein Tom37 are components of preprotein import complexes of the ...