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zipt-1 Zrt (ZRT), Irt- (IRT-) like Protein Transporter [ Caenorhabditis elegans ]

Gene ID: 173376, updated on 18-Sep-2024

Summary

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Official Symbol
zipt-1
Official Full Name
Zrt (ZRT), Irt- (IRT-) like Protein Transporter
Primary source
WormBase:WBGene00009286
Locus tag
CELE_F31C3.4
See related
AllianceGenome:WB:WBGene00009286
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in zinc ion transmembrane transport. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to several human genes including SLC39A1 (solute carrier family 39 member 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See zipt-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003279.8 (15050797..15052420, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene PAP-associated domain-containing protein Neighboring gene Peptidyl-prolyl cis-trans isomerase 5 Neighboring gene FMP27/BLTP2/Hobbit GFWDK motif-containing RBG unit domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Protein kinase domain-containing protein Neighboring gene putative DNA replication complex GINS protein PSF2 Neighboring gene rRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables metal ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in metal ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in zinc ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in zinc ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Zrt (ZRT), Irt- (IRT-) like Protein Transporter
NP_493626.1
  • Product from WormBase gene class zipt;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    15050797..15052420 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_061225.7 → NP_493626.1  Zrt (ZRT), Irt- (IRT-) like Protein Transporter [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_493626.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O62192
    Conserved Domains (1) summary
    pfam02535
    Location:32 → 308
    Zip; ZIP Zinc transporter
Nucleotide Protein
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