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K10B4.3 Protein melted homolog [ Caenorhabditis elegans ]

Gene ID: 173397, updated on 2-Nov-2024

Summary

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Official Symbol
K10B4.3
Official Full Name
Protein melted homolog
Primary source
WormBase:WBGene00019615
Locus tag
CELE_K10B4.3
See related
AllianceGenome:WB:WBGene00019615
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable phosphatidylinositol-5-phosphate binding activity. Predicted to be involved in regulation of signal transduction. Predicted to be active in plasma membrane. Orthologous to human VEPH1 (ventricular zone expressed PH domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See K10B4.3 in Genome Data Viewer
Location:
chromosome: II
Exon count:
10
Sequence:
Chromosome: II; NC_003280.10 (114428..121221, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene PDZ domain-containing protein Neighboring gene Cationic amino acid transporter C-terminal domain-containing protein Neighboring gene Ntox44 domain-containing protein;Peptidase S1 domain-containing protein Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene Neuromedin U receptor homolog nmur-2 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables phosphatidylinositol-5-phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Protein melted homolog
NP_493664.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    114428..121221 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_061263.5 → NP_493664.2  Protein melted homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_493664.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O17237
    Conserved Domains (2) summary
    pfam00169
    Location:759 → 864
    PH; PH domain
    cl17171
    Location:757 → 869
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O17237.3

Gene LinkOut

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