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mps-2 MiRP K channel accessory Subunit [ Caenorhabditis elegans ]

Gene ID: 173419, updated on 2-Nov-2024

Summary

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Official Symbol
mps-2
Official Full Name
MiRP K channel accessory Subunit
Primary source
WormBase:WBGene00019282
Locus tag
CELE_K01A2.8
See related
AllianceGenome:WB:WBGene00019282
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables potassium channel regulator activity. Involved in long-term memory; regulation of chemotaxis; and regulation of potassium ion transport. Predicted to be located in membrane. Is expressed in several structures, including coelomocyte; enteric muscle; intestine; lateral ganglion; and rectal muscle. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See mps-2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003280.10 (309479..312157, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene AB hydrolase-1 domain-containing protein Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene DUF2231 domain-containing protein;Transmembrane protein Neighboring gene pseudo Neighboring gene MiRP K channel accessory Subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dual Role of an mps-2/KCNE-Dependent Pathway in Long-Term Memory and Age-Dependent Memory Decline. Fenyves BG, et al. Curr Biol, 2021 Feb 8. PMID 33259792
  2. An evolutionarily conserved family of accessory subunits of K+ channels. Cai SQ, et al. Cell Biochem Biophys, 2006. PMID 16943626
  3. A family of K+ channel ancillary subunits regulate taste sensitivity in Caenorhabditis elegans. Park KH, et al. J Biol Chem, 2005 Jun 10. PMID 15799965
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables potassium channel regulator activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in long-term memory IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of chemotaxis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of potassium ion transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of potassium ion transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
MiRP K channel accessory Subunit
NP_001033335.1
  • Product from WormBase gene class mps;
    Confirmed by transcript evidence
NP_001379579.1
  • Product from WormBase gene class mps;
    Confirmed by transcript evidence
NP_001379580.1
  • Product from WormBase gene class mps;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    309479..312157 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001392992.1 → NP_001379580.1  MiRP K channel accessory Subunit [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q86S20

  2. NM_001392991.1 → NP_001379579.1  MiRP K channel accessory Subunit [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q56VR8, Q9TZ55

  3. NM_001038246.6 → NP_001033335.1  MiRP K channel accessory Subunit [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001033335.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q56VR8, Q56VR9
Nucleotide Protein
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