C24H12.4 Helicase C-terminal domain-containing protein;RNA helicase [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: C24H12.4
Official Full Name: Helicase C-terminal domain-containing protein;RNA helicase
Primary source: WormBase:WBGene00016073
Locus tag: CELE_C24H12.4
See related: AllianceGenome:WB:WBGene00016073
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable several functions, including ATP binding activity; RNA helicase activity; and nucleic acid binding activity. Predicted to be active in nucleolus. Orthologous to human DDX56 (DEAD-box helicase 56). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See C24H12.4 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 8

Sequence:: Chromosome: II; NC_003280.10 (411222..416629)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C24H12.5 (e-PCR)
- UniSTS:313733

C24H12.4 (e-PCR)
- UniSTS:308628

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables RNA helicase activity	IEA Inferred from Electronic Annotation more info
enables helicase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Helicase C-terminal domain-containing protein;RNA helicase

NP_001300515.1

Confirmed by transcript evidence

NP_001300516.1

Partially confirmed by transcript evidence

NP_740966.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

411222..416629

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_170970.7 → NP_740966.1 RNA helicase [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_740966.1

Status: REVIEWED

UniProtKB/TrEMBL

O17157

Conserved Domains (1) summary

COG0513
Location:46 → 561

SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
NM_001313586.3 → NP_001300515.1 Helicase C-terminal domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A0K3AQY8

Conserved Domains (1) summary

cd18787
Location:38 → 207

SF2_C_DEAD; C-terminal helicase domain of the DEAD box helicases
NM_001313587.3 → NP_001300516.1 Helicase C-terminal domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A0K3AUI3