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tomm-22 Mitochondrial import receptor subunit TOM22 homolog [ Caenorhabditis elegans ]

Gene ID: 173436, updated on 2-Nov-2024

Summary

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Official Symbol
tomm-22
Official Full Name
Mitochondrial import receptor subunit TOM22 homolog
Primary source
WormBase:WBGene00021133
Locus tag
CELE_W10D9.5
See related
AllianceGenome:WB:WBGene00021133
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in intracellular protein transport. Predicted to be located in mitochondrial outer membrane. Orthologous to human TOMM22 (translocase of outer mitochondrial membrane 22). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tomm-22 in Genome Data Viewer
Location:
chromosome: II
Exon count:
2
Sequence:
Chromosome: II; NC_003280.10 (468374..470475, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene MKRN2 opposite strand protein-like C-terminal domain-containing protein Neighboring gene Nuclear transcription factor Y subunit nfyb-1 Neighboring gene ncRNA Neighboring gene 26S rRNA (cytosine-C(5))-methyltransferase nsun-1 Neighboring gene G_PROTEIN_RECEP_F2_4 domain-containing protein Neighboring gene NLE domain-containing protein;WD_REPEATS_REGION domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The evolutionarily conserved ESRE stress response network is activated by ROS and mitochondrial damage. Tjahjono E, et al. BMC Biol, 2020 Jun 29. PMID 32600387, Free PMC Article
  2. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
  3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Mitochondrial import receptor subunit TOM22 homolog
NP_001368584.1
  • Confirmed by transcript evidence
NP_493741.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    468374..470475 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_061340.6 → NP_493741.1  Mitochondrial import receptor subunit TOM22 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_493741.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A0M7RDR0, O17287
    Conserved Domains (1) summary
    cl11522
    Location:6 → 92
    Tom22; Mitochondrial import receptor subunit Tom22

  2. NM_001381316.1 → NP_001368584.1  Mitochondrial import receptor subunit TOM22 homolog [Caenorhabditis elegans]

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O17287.1

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