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slc-36.2 Amino acid transporter transmembrane domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 173442, updated on 2-Nov-2024

Summary

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Official Symbol
slc-36.2
Official Full Name
Amino acid transporter transmembrane domain-containing protein
Primary source
WormBase:WBGene00020837
Locus tag
CELE_T27A1.5
See related
AllianceGenome:WB:WBGene00020837
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be located in membrane. Predicted to be active in vacuolar membrane. Human ortholog(s) of this gene implicated in iminoglycinuria. Orthologous to several human genes including SLC36A1 (solute carrier family 36 member 1); SLC36A2 (solute carrier family 36 member 2); and SLC36A3 (solute carrier family 36 member 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See slc-36.2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
6
Sequence:
Chromosome: II; NC_003280.10 (522602..525981)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Serpentine Receptor, class H Neighboring gene T-box protein 12 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neighboring gene F-box associated domain-containing protein Neighboring gene F-box domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Organelle proteomic profiling reveals lysosomal heterogeneity in association with longevity. Yu Y, et al. Elife, 2024 Jan 19. PMID 38240316, Free PMC Article
  2. Lysosome activity is modulated by multiple longevity pathways and is important for lifespan extension in C. elegans. Sun Y, et al. Elife, 2020 Jun 2. PMID 32482227, Free PMC Article
  3. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables L-amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in L-alpha-amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in vacuolar membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Amino acid transporter transmembrane domain-containing protein
NP_001040812.1
  • Confirmed by transcript evidence
NP_001040813.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    522602..525981
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001047347.4 → NP_001040812.1  Amino acid transporter transmembrane domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001040812.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G4SQY7
    Conserved Domains (1) summary
    cl00456
    Location:37 → 441
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  2. NM_001047348.4 → NP_001040813.1  Amino acid transporter transmembrane domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001040813.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O17275
    Conserved Domains (1) summary
    cl00456
    Location:19 → 336
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
Nucleotide Protein
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Gene LinkOut

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