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mlt-10 MLt-TeN (Mlt-10) related [ Caenorhabditis elegans ]

Gene ID: 173445, updated on 12-Jun-2024

Summary

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Gene symbol
mlt-10
Gene description
MLt-TeN (Mlt-10) related
Locus tag
CELE_C09E8.3
See related
AllianceGenome:WB:WBGene00015646
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle and epidermis development. Located in extracellular space. Is expressed in hypodermal cell and pharyngeal epithelial cell. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See mlt-10 in Genome Data Viewer
Location:
chromosome: II
Exon count:
8
Sequence:
Chromosome: II; NC_003280.10 (546705..552032)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neighboring gene F-box associated domain-containing protein Neighboring gene F-box domain-containing protein Neighboring gene LIPaSe related;Triacylglycerol lipase Neighboring gene Sodium-and chloride-dependent glycine transporter 2 Neighboring gene Uncharacterized protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The mir-84 and let-7 paralogous microRNA genes of Caenorhabditis elegans direct the cessation of molting via the conserved nuclear hormone receptors NHR-23 and NHR-25. Hayes GD, et al. Development, 2006 Dec. PMID 17065234
  2. MLT-10 defines a family of DUF644 and proline-rich repeat proteins involved in the molting cycle of Caenorhabditis elegans. Meli VS, et al. Mol Biol Cell, 2010 May 15. PMID 20335506, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. mlt-10 defines a family of DUF644 and proline-rich repeat proteins involved in the molting cycle of Caenorhabditis elegans.
    Title: MLT-10 defines a family of DUF644 and proline-rich repeat proteins involved in the molting cycle of Caenorhabditis elegans.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in cuticle development involved in collagen and cuticulin-based cuticle molting cycle IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in epidermis development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
MLt-TeN (Mlt-10) related
NP_493755.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    546705..552032
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_061354.5 → NP_493755.1  MLt-TeN (Mlt-10) related [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_493755.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O76555
    Conserved Domains (1) summary
    pfam04870
    Location:189 → 502
    Moulting_cycle; Moulting cycle
Nucleotide Protein
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