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ins-31 INSulin related [ Caenorhabditis elegans ]

Gene ID: 173660, updated on 2-Nov-2024

Summary

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Official Symbol
ins-31
Official Full Name
INSulin related
Primary source
WormBase:WBGene00002114
Locus tag
CELE_T10D4.4
See related
AllianceGenome:WB:WBGene00002114
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Is expressed in coelomocyte and male gonad. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ins-31 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003280.10 (3127041..3127831)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Serpentine Receptor, class H Neighboring gene INSulin related Neighboring gene GH18 domain-containing protein Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. GABAergic synapses suppress intestinal innate immunity via insulin signaling in Caenorhabditis elegans. Zheng Z, et al. Proc Natl Acad Sci U S A, 2021 May 18. PMID 33972423, Free PMC Article
  2. Intestine-to-neuronal signaling alters risk-taking behaviors in food-deprived Caenorhabditis elegans. Matty MA, et al. PLoS Genet, 2022 May. PMID 35511794, Free PMC Article
  3. Males shorten the life span of C. elegans hermaphrodites via secreted compounds. Maures TJ, et al. Science, 2014 Jan 31. PMID 24292626, Free PMC Article
  4. Insulin worms its way into the spotlight. Nelson DW, et al. Genes Dev, 2003 Apr 1. PMID 12670864
  5. Genome-wide analysis of sex-enriched gene expression during C. elegans larval development. Thoemke K, et al. Dev Biol, 2005 Aug 15. PMID 15987632

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables hormone activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
INSulin related
NP_494454.1
  • Product from WormBase gene class ins;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    3127041..3127831
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_062053.3 → NP_494454.1  INSulin related [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_494454.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9TZF3
    Conserved Domains (1) summary
    pfam03488
    Location:93 → 142
    Ins_beta; Nematode insulin-related peptide beta type
Nucleotide Protein
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