R11F4.1 putative glycerol kinase [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: R11F4.1
Official Full Name: putative glycerol kinase
Primary source: WormBase:WBGene00020007
Locus tag: CELE_R11F4.1
See related: AllianceGenome:WB:WBGene00020007
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable glycerol kinase activity. Predicted to be involved in glycerol metabolic process; glycerol-3-phosphate biosynthetic process; and triglyceride metabolic process. Predicted to be active in mitochondrion. Is expressed in body wall musculature; gonadal sheath cell; intestine; and pharynx. Human ortholog(s) of this gene implicated in glycerol kinase deficiency. Orthologous to human GK (glycerol kinase); GK2 (glycerol kinase 2); and GK3 (glycerol kinase 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See R11F4.1 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 5

Sequence:: Chromosome: II; NC_003280.10 (4091930..4094349)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

R11F4.1 (e-PCR)
- UniSTS:311577

STS2-129 (e-PCR)
- UniSTS:241796

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables glycerol kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glycerol kinase activity	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in glycerol catabolic process	IEA Inferred from Electronic Annotation more info
involved_in glycerol metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in glycerol metabolic process	IEA Inferred from Electronic Annotation more info
involved_in glycerol-3-phosphate biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in glycerol-3-phosphate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in triglyceride metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: putative glycerol kinase

NP_494721.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

4091930..4094349

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_062320.5 → NP_494721.1 putative glycerol kinase [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_494721.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q21944

Conserved Domains (2) summary

cd07769
Location:3 → 491

FGGY_GK; Glycerol kinases; a subfamily of the FGGY family of carbohydrate kinases

TIGR01311
Location:3 → 500

glycerol_kin; glycerol kinase