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T12C9.7 CYCLIN domain-containing protein;Cyclin-like domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 173782, updated on 2-Nov-2024

Summary

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Official Symbol
T12C9.7
Official Full Name
CYCLIN domain-containing protein;Cyclin-like domain-containing protein
Primary source
WormBase:WBGene00020461
Locus tag
CELE_T12C9.7
See related
AllianceGenome:WB:WBGene00020461
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in G1/S transition of mitotic cell cycle. Predicted to be part of cyclin A2-CDK2 complex. Predicted to be active in cytoplasm; microtubule organizing center; and nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See T12C9.7 in Genome Data Viewer
Location:
chromosome: II
Exon count:
9
Sequence:
Chromosome: II; NC_003280.10 (4458258..4460951, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Potassium channel domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Vacuolar protein sorting-associated protein 18 homolog Neighboring gene N-acetyl-D-glucosamine kinase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cyclin-dependent protein serine/threonine kinase regulator activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in G1/S transition of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in mitotic cell cycle phase transition IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of cyclin A2-CDK2 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in microtubule organizing center IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
CYCLIN domain-containing protein;Cyclin-like domain-containing protein
NP_001122636.1
  • Confirmed by transcript evidence
NP_001122637.1
  • Confirmed by transcript evidence
NP_001368016.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    4458258..4460951 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001129164.3 → NP_001122636.1  CYCLIN domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122636.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2L0L4
    Conserved Domains (2) summary
    smart00385
    Location:163 → 248
    CYCLIN; domain present in cyclins, TFIIB and Retinoblastoma
    cd20537
    Location:258 → 321
    CYCLIN_CCNO-like_rpt2; second cyclin box found in cyclin-O (CCNO) and similar proteins

  2. NM_001129165.6 → NP_001122637.1  CYCLIN domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122637.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A9Z1K4
    Conserved Domains (2) summary
    smart00385
    Location:163 → 248
    CYCLIN; domain present in cyclins, TFIIB and Retinoblastoma
    cd20537
    Location:258 → 321
    CYCLIN_CCNO-like_rpt2; second cyclin box found in cyclin-O (CCNO) and similar proteins

  3. NM_001381391.2 → NP_001368016.1  Cyclin-like domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2L0L5
    Conserved Domains (1) summary
    cl40454
    Location:171 → 263
    CYCLIN_SF; Cyclin box fold superfamily
Nucleotide Protein
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