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hmg-11 HMG [ Caenorhabditis elegans ]

Gene ID: 173805, updated on 2-Nov-2024

Summary

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Official Symbol
hmg-11
Official Full Name
HMG
Primary source
WormBase:WBGene00001976
Locus tag
CELE_T05A7.4
See related
AllianceGenome:WB:WBGene00001976
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA binding activity. Is expressed in several structures, including anal depressor muscle; egg-laying apparatus; excretory cell; hypodermis; and nervous system. Human ortholog(s) of this gene implicated in Silver-Russell syndrome; leiomyoma; lipoma; and ovarian cancer. Orthologous to human HMGA2 (high mobility group AT-hook 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See hmg-11 in Genome Data Viewer
Location:
chromosome: II
Exon count:
2
Sequence:
Chromosome: II; NC_003280.10 (4673085..4673746)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Alpha-(1,3)-fucosyltransferase fut-5 Neighboring gene Protein kinase domain-containing protein Neighboring gene C-type lectin domain-containing protein Neighboring gene CUB domain-containing protein Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. SnAvi--a new tandem tag for high-affinity protein-complex purification. Schäffer U, et al. Nucleic Acids Res, 2010 Apr. PMID 20047968, Free PMC Article
  2. H3K23me2 is a new heterochromatic mark in Caenorhabditis elegans. Vandamme J, et al. Nucleic Acids Res, 2015 Nov 16. PMID 26476455, Free PMC Article
  3. Maternal H3K36 and H3K27 HMTs protect germline development via regulation of the transcription factor LIN-15B. Cockrum CS, et al. Elife, 2022 Aug 3. PMID 35920536, Free PMC Article
  4. The TORC1 phosphoproteome in C. elegans reveals roles in transcription and autophagy. Sewell AK, et al. iScience, 2022 May 20. PMID 35479415, Free PMC Article
  5. Stable-isotope labeling with amino acids in nematodes. Larance M, et al. Nat Methods, 2011 Aug 28. PMID 21874007, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
HMG
NP_494825.1
  • Product from WormBase gene class hmg;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    4673085..4673746
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_062424.10 → NP_494825.1  HMG [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_494825.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EEL9
    Conserved Domains (1) summary
    PRK07003
    Location:22 → 123
    PRK07003; DNA polymerase III subunits gamma and tau; Validated
Nucleotide Protein
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