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F41C3.8 MARVEL domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 173814, updated on 2-Nov-2024

Summary

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Official Symbol
F41C3.8
Official Full Name
MARVEL domain-containing protein
Primary source
WormBase:WBGene00018274
Locus tag
CELE_F41C3.8
See related
AllianceGenome:WB:WBGene00018274
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be located in membrane. Is expressed in intestine; neurons; and pharyngeal muscle cell. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See F41C3.8 in Genome Data Viewer
Location:
chromosome: II
Exon count:
7
Sequence:
Chromosome: II; NC_003280.10 (4716046..4718536)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Staphylococcal nuclease domain-containing protein 1 Neighboring gene Pre-rRNA-processing protein TSR1 homolog Neighboring gene E3 ubiquitin-protein ligase Neighboring gene Transthyretin-like family protein Neighboring gene Ovule protein;WD_REPEATS_REGION domain-containing protein Neighboring gene Nucleotide-diphospho-sugar transferase domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Shapira M, et al. Proc Natl Acad Sci U S A, 2006 Sep 19. PMID 16968778, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in defense response to Gram-negative bacterium IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in innate immune response HEP PubMed 
involved_in innate immune response IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
MARVEL domain-containing protein
NP_001040776.1
  • Confirmed by transcript evidence
NP_001040777.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    4716046..4718536
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001047312.3 → NP_001040777.1  MARVEL domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001040777.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q27GU4
    Conserved Domains (1) summary
    cl00337
    Location:164 → 260
    PT_UbiA; UbiA family of prenyltransferases (PTases)

  2. NM_001047311.3 → NP_001040776.1  MARVEL domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001040776.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q20259
    Conserved Domains (1) summary
    cl00337
    Location:132 → 228
    PT_UbiA; UbiA family of prenyltransferases (PTases)
Nucleotide Protein
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