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btbd-10 BTB domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 173847, updated on 2-Nov-2024

Summary

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Official Symbol
btbd-10
Official Full Name
BTB domain-containing protein
Primary source
WormBase:WBGene00019888
Locus tag
CELE_R05F9.1
See related
AllianceGenome:WB:WBGene00019888
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in signal transduction. Predicted to be active in cytoplasm. Is expressed in several structures, including enteric muscle; hypodermal cell; nervous system; pharyngeal-intestinal valve; and reproductive system. Orthologous to human BTBD10 (BTB domain containing 10) and KCTD20 (potassium channel tetramerization domain containing 20). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See btbd-10 in Genome Data Viewer
Location:
chromosome: II
Exon count:
10
Sequence:
Chromosome: II; NC_003280.10 (4905008..4911835)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene SGTA homodimerization domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene snRNA-activating protein complex subunit 1 Neighboring gene P-type domain-containing protein Neighboring gene Major sperm protein 19/31/40/45/50/51/53/59/61/65/81/113/142 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Reduced expression of BTBD10, an Akt activator, leads to motor neuron death. Nawa M, et al. Cell Death Differ, 2012 Aug. PMID 22388351, Free PMC Article
  2. Genome sequencing of C. elegans balancer strains reveals previously unappreciated complex genomic rearrangements. Maroilley T, et al. Genome Res, 2023 Jan. PMID 36617680, Free PMC Article
  3. Protein interaction mapping in C. elegans using proteins involved in vulval development. Walhout AJ, et al. Science, 2000 Jan 7. PMID 10615043
  4. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Reboul J, et al. Nat Genet, 2003 May. PMID 12679813
  5. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
BTB domain-containing protein
NP_001367754.1
  • Confirmed by transcript evidence
NP_001379870.1
  • Confirmed by transcript evidence
NP_740981.1
  • Confirmed by transcript evidence
NP_740982.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    4905008..4911835
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_170983.7 → NP_740981.1  BTB domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_740981.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q21747
    Conserved Domains (2) summary
    pfam05109
    Location:79 → 181
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    cd18318
    Location:232 → 328
    BTB_POZ_KCTD20-like; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium channel tetramerization domain-containing protein 20 (KCTD20) and BTB/POZ domain-containing protein 10 (BTBD10)

  2. NM_001381405.1 → NP_001367754.1  BTB domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7JP41

  3. NM_001393055.1 → NP_001379870.1  BTB domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q86NF2
    Conserved Domains (1) summary
    cd18318
    Location:31 → 127
    BTB_POZ_KCTD20-like; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium channel tetramerization domain-containing protein 20 (KCTD20) and BTB/POZ domain-containing protein 10 (BTBD10)

  4. NM_170984.4 → NP_740982.1  BTB domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_740982.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q21748
    Conserved Domains (1) summary
    cd18318
    Location:135 → 231
    BTB_POZ_KCTD20-like; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium channel tetramerization domain-containing protein 20 (KCTD20) and BTB/POZ domain-containing protein 10 (BTBD10)
Nucleotide Protein
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