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ZK546.2 Leucine-rich repeat-containing protein 57 [ Caenorhabditis elegans ]

Gene ID: 173855, updated on 2-Nov-2024

Summary

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Official Symbol
ZK546.2
Official Full Name
Leucine-rich repeat-containing protein 57
Primary source
WormBase:WBGene00022759
Locus tag
CELE_ZK546.2
See related
AllianceGenome:WB:WBGene00022759
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be active in cytoplasm. Orthologous to human LRRC57 (leucine rich repeat containing 57). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ZK546.2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003280.10 (4946027..4948070)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Secreted protein Neighboring gene ncRNA Neighboring gene Mediator of RNA polymerase II transcription subunit 4 Neighboring gene Ribosomal RNA-processing protein 14/surfeit locus protein 6 C-terminal domain-containing protein;SURF6 domain-containing protein Neighboring gene Peptidase S1 domain-containing protein Neighboring gene Zygote defective protein 12

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article
  2. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Leucine-rich repeat-containing protein 57
NP_001380033.1
  • Confirmed by transcript evidence
NP_740983.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    4946027..4948070
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_170985.5 → NP_740983.2  Leucine-rich repeat-containing protein 57 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_740983.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q23526, Q23527
    Conserved Domains (4) summary
    cd00116
    Location:208 → 460
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:264 → 286
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:65 → 107
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:308 → 364
    LRR_8; Leucine rich repeat

  2. NM_001393057.1 → NP_001380033.1  Leucine-rich repeat-containing protein 57 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95PW8
    Conserved Domains (2) summary
    COG4886
    Location:37 → 209
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:40 → 62
    LRR_RI; leucine-rich repeat [structural motif]

RNA

  1. NR_151581.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
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