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fbxl-3 Putative RNA-binding protein EEED8.10 [ Caenorhabditis elegans ]

Gene ID: 173919, updated on 2-Nov-2024

Summary

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Official Symbol
fbxl-3
Official Full Name
Putative RNA-binding protein EEED8.10
Primary source
WormBase:WBGene00017138
Locus tag
CELE_EEED8.10
See related
AllianceGenome:WB:WBGene00017138
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable RNA binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human FBXL13 (F-box and leucine rich repeat protein 13). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See fbxl-3 in Genome Data Viewer
Location:
chromosome: II
Exon count:
10
Sequence:
Chromosome: II; NC_003280.10 (5395892..5398902, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene BRCA1-associated protein homolog 2 Neighboring gene Serine/threonine-protein kinase pink-1, mitochondrial Neighboring gene putative pre-mRNA-splicing factor ATP-dependent RNA helicase mog-5 Neighboring gene C-type lectin domain-containing protein 141 Neighboring gene Putative RNA-binding protein EEED8.12

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The F-box protein family. Kipreos ET, et al. Genome Biol, 2000. PMID 11178263, Free PMC Article
  2. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
  3. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
  4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of SCF ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Putative RNA-binding protein EEED8.10
NP_001040757.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    5395892..5398902 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001047292.5 → NP_001040757.1  Putative RNA-binding protein EEED8.10 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001040757.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q09299, Q2V4U6, Q7JPI7, Q8IG36
    Conserved Domains (4) summary
    cd09293
    Location:394 → 615
    AMN1; Antagonist of mitotic exit network protein 1
    COG0724
    Location:101 → 273
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd00590
    Location:114 → 197
    RRM_SF; RNA recognition motif (RRM) superfamily
    sd00034
    Location:344 → 368
    LRR_AMN1; leucine-rich repeat [structural motif]

RNA

  1. NR_003153.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q09299.3

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