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lys-8 LYSozyme [ Caenorhabditis elegans ]

Gene ID: 173944, updated on 2-Nov-2024

Summary

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Official Symbol
lys-8
Official Full Name
LYSozyme
Primary source
WormBase:WBGene00003097
Locus tag
CELE_C17G10.5
See related
AllianceGenome:WB:WBGene00003097
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in nematode pharyngeal gland morphogenesis. Is expressed in intestine; neurons; and pharyngeal gland cell. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See lys-8 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003280.10 (5586178..5587651)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene THAP-type domain-containing protein Neighboring gene Tyrosine-protein phosphatase cdc-14 Neighboring gene Cns1/TTC4 wheel domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Indole produced during dysbiosis mediates host-microorganism chemical communication. Yang RQ, et al. Elife, 2023 Nov 21. PMID 37987602, Free PMC Article
  2. Paeoniflorin increases the survival of Pseudomonas aeruginosa infected Caenorhabditis elegans at the immunosuppression stage by activating PMK-1, BAR-1, and EGL-1 signals. Zhang L, et al. Arch Pharm Res, 2023 Jul. PMID 37535304
  3. GPA-9 is a novel regulator of innate immunity against Escherichia coli foods in adult Caenorhabditis elegans. Hahm JH, et al. Aging Cell, 2011 Apr. PMID 21108728
  4. Antimicrobial proteins in the response to graphene oxide in Caenorhabditis elegans. Ren M, et al. Nanotoxicology, 2017 May. PMID 28490217
  5. Biosafety assessment of Acinetobacter strains isolated from the Three Gorges Reservoir region in nematode Caenorhabditis elegans. Deng Y, et al. Sci Rep, 2021 Oct 5. PMID 34611259, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in nematode pharyngeal gland morphogenesis IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in response to stress IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
LYSozyme
NP_495083.1
  • Product from WormBase gene class lys;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    5586178..5587651
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_062682.6 → NP_495083.1  LYSozyme [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495083.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q09975
    Conserved Domains (1) summary
    cd06416
    Location:56 → 258
    GH25_Lys1-like; Lys-1 is a lysozyme encoded by the Caenorhabditis elegans lys-1 gene. This gene is one of a several lysozyme genes upregulated upon infection by the Gram-negative bacterial pathogen Serratia marcescens. Lys-1 contains a glycosyl hydrolase family 25 ...
Nucleotide Protein
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