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tex-2 SMP-LTD domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 173997, updated on 2-Nov-2024

Summary

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Official Symbol
tex-2
Official Full Name
SMP-LTD domain-containing protein
Primary source
WormBase:WBGene00018872
Locus tag
CELE_F55C12.5
See related
AllianceGenome:WB:WBGene00018872
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable lipid binding activity. Predicted to be involved in lipid transport. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Is expressed in AIYL and AIYR. Orthologous to human TEX2 (testis expressed 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tex-2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
10
Sequence:
Chromosome: II; NC_003280.10 (5867252..5873614, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene UPAR/Ly6 domain-containing protein Neighboring gene Activin_recp domain-containing protein Neighboring gene DUF1248 domain-containing protein Neighboring gene Transglycosylase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. PDZD-8 and TEX-2 regulate endosomal PI(4,5)P(2) homeostasis via lipid transport to promote embryogenesis in C. elegans. Jeyasimman D, et al. Nat Commun, 2021 Oct 18. PMID 34663803, Free PMC Article
  2. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables lipid binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in lipid transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
SMP-LTD domain-containing protein
NP_495171.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    5867252..5873614 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_062770.6 → NP_495171.1  SMP-LTD domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495171.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2L079, H2L080
Nucleotide Protein
Heading Accession and Version

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