plpp-1.2 Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein;Phospholipid phosphatase homolog 1.2 homolog [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: plpp-1.2
Official Full Name: Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein;Phospholipid phosphatase homolog 1.2 homolog
Primary source: WormBase:WBGene00020895
Locus tag: CELE_T28D9.3
See related: AllianceGenome:WB:WBGene00020895
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable phosphatidate phosphatase activity. Predicted to be involved in phospholipid dephosphorylation; phospholipid metabolic process; and signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human PLPP3 (phospholipid phosphatase 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See plpp-1.2 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 10

Sequence:: Chromosome: II; NC_003280.10 (6485476..6488810)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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General gene information

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Markers

T28D9.3 (e-PCR)
- UniSTS:311059

T28D9.9 (e-PCR)
- UniSTS:317210

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables phosphatidate phosphatase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in phospholipid dephosphorylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in phospholipid metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in phospholipid metabolic process	IEA Inferred from Electronic Annotation more info
involved_in signal transduction	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein;Phospholipid phosphatase homolog 1.2 homolog

NP_001022377.1

Partially confirmed by transcript evidence

NP_001022378.1

Confirmed by transcript evidence

NP_001122646.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

6485476..6488810

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001129174.4 → NP_001122646.1 Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001122646.1

Status: REVIEWED

UniProtKB/TrEMBL

A8WFI4

Conserved Domains (1) summary

cd03384
Location:138 → 287

PAP2_wunen; PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the ...
NM_001027207.5 → NP_001022378.1 Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001022378.1

Status: REVIEWED

UniProtKB/TrEMBL

H2L0E9

Conserved Domains (1) summary

cd03384
Location:122 → 271

PAP2_wunen; PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the ...
NM_001027206.2 → NP_001022377.1 Phospholipid phosphatase homolog 1.2 homolog [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001022377.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q10022

Conserved Domains (1) summary

cd03384
Location:121 → 270

PAP2_wunen; PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the ...