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dnj-8 DnaJ homolog subfamily C member 16;Thioredoxin domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 174093, updated on 2-Nov-2024

Summary

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Official Symbol
dnj-8
Official Full Name
DnaJ homolog subfamily C member 16;Thioredoxin domain-containing protein
Primary source
WormBase:WBGene00001026
Locus tag
CELE_C56C10.13
See related
AllianceGenome:WB:WBGene00001026
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in autophagy. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human DNAJC16 (DnaJ heat shock protein family (Hsp40) member C16). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See dnj-8 in Genome Data Viewer
Location:
chromosome: II
Exon count:
7
Sequence:
Chromosome: II; NC_003280.10 (6594382..6598080, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Charged multivesicular body protein 4b Neighboring gene 45 kDa calcium-binding protein Neighboring gene TPR_REGION domain-containing protein Neighboring gene Ectopic P granules protein 5 Neighboring gene Vacuolar protein sorting-associated protein 33B Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ERdj8 governs the size of autophagosomes during the formation process. Yamamoto YH, et al. J Cell Biol, 2020 Aug 3. PMID 32492081, Free PMC Article
  2. A Differentiation Transcription Factor Establishes Muscle-Specific Proteostasis in Caenorhabditis elegans. Bar-Lavan Y, et al. PLoS Genet, 2016 Dec. PMID 28036392, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in autophagy IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DnaJ homolog subfamily C member 16;Thioredoxin domain-containing protein
NP_001040753.1
  • Confirmed by transcript evidence
NP_001040754.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    6594382..6598080 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001047288.5 → NP_001040753.1  DnaJ homolog subfamily C member 16 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001040753.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95QQ1
    Conserved Domains (2) summary
    cd02963
    Location:118 → 229
    TRX_DnaJ; TRX domain, DnaJ domain containing protein family; composed of uncharacterized proteins of about 500-800 amino acids, containing an N-terminal DnaJ domain followed by one redox active TRX domain. DnaJ is a member of the 40 kDa heat-shock protein (Hsp40) ...
    TIGR02349
    Location:22 → 86
    DnaJ_bact; chaperone protein DnaJ

  2. NM_001047289.6 → NP_001040754.1  Thioredoxin domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001040754.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B2MZA7
    Conserved Domains (2) summary
    COG0484
    Location:2 → 23
    DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
    cd02963
    Location:55 → 166
    TRX_DnaJ; TRX domain, DnaJ domain containing protein family; composed of uncharacterized proteins of about 500-800 amino acids, containing an N-terminal DnaJ domain followed by one redox active TRX domain. DnaJ is a member of the 40 kDa heat-shock protein (Hsp40) ...
Nucleotide Protein
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