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acer-1 Acetyl-CoA hydrolase [ Caenorhabditis elegans ]

Gene ID: 174128, updated on 2-Nov-2024

Summary

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Official Symbol
acer-1
Official Full Name
Acetyl-CoA hydrolase
Primary source
WormBase:WBGene00016630
Locus tag
CELE_C44B7.10
See related
AllianceGenome:WB:WBGene00016630
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable acetate CoA-transferase activity and acetyl-CoA hydrolase activity. Predicted to be involved in acetate metabolic process. Is expressed in several structures, including germ line. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See acer-1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
4
Sequence:
Chromosome: II; NC_003280.10 (6888553..6890400, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Peroxisomal Membrane Protein related Neighboring gene ncRNA Neighboring gene Adenosine deaminase-like protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. NatB domain-containing CRA-1 antagonizes hydrolase ACER-1 linking acetyl-CoA metabolism to the initiation of recombination during C. elegans meiosis. Gao J, et al. PLoS Genet, 2015 Mar. PMID 25768301, Free PMC Article
  2. A UPR-independent infection-specific role for a BiP/GRP78 protein in the control of antimicrobial peptide expression in C. elegans epidermis. Couillault C, et al. Virulence, 2012 May 1. PMID 22546897, Free PMC Article
  3. Robust co-immunoprecipitation with mass spectrometry for Caenorhabditis elegans using solid-phase enhanced sample preparation. Baytek G, et al. Biotechniques, 2022 May. PMID 35297663
  4. Conservation of caspase substrates across metazoans suggests hierarchical importance of signaling pathways over specific targets and cleavage site motifs in apoptosis. Crawford ED, et al. Cell Death Differ, 2012 Dec. PMID 22918439, Free PMC Article
  5. CCAR-1 works together with the U2AF large subunit UAF-1 to regulate alternative splicing. Lugano DI, et al. RNA Biol, 2024 Jan. PMID 38126797, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables CoA-transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables acetate CoA-transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables acetyl-CoA hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in acetate metabolic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Acetyl-CoA hydrolase
NP_495409.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    6888553..6890400 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063008.8 → NP_495409.3  Acetyl-CoA hydrolase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495409.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q18599
    Conserved Domains (1) summary
    COG0427
    Location:39 → 460
    ACH1; Acyl-CoA hydrolase [Energy production and conversion]
Nucleotide Protein
Heading Accession and Version

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